[ECRIN standard requirements for good clinical practices-compliant data management in multinational clinical trials].

Référentiel ECRIN pour la conformité aux bonnes pratiques de gestion des données des essais cliniques multinationaux.
Academic studies Data management Gestion de données Information technology Quality reference Référentiel qualité Systèmes d’information Études cliniques institutionnelles

Journal

Therapie
ISSN: 1958-5578
Titre abrégé: Therapie
Pays: France
ID NLM: 0420544

Informations de publication

Date de publication:
Historique:
received: 09 03 2015
accepted: 28 05 2015
medline: 15 11 2016
pubmed: 15 11 2016
entrez: 15 11 2016
Statut: ppublish

Résumé

Clinical studies involve an increasing amount of data collection and management. However, there is no specific quality standard sufficiently practical, in free access, and open for data management and the underlying IT-infrastructure in academic units. European Clinical Research Infrastructures Network (ECRIN) published standard requirements for certified data management units. We present a French version of these standards. A group of experts produced the standards, by consensus. The first version was revised after two pilot audits for data centre certification were performed. The revised version includes 21 lists of five to ten standards, in three groups: information technologies, data management (DM) and "general". These standards offer a clear description of DM and IT requirements for clinical studies. Initially created for ECRIN certification purposes, they offer a very useful reference for academic DM structures.

Identifiants

pubmed: 27839710
pii: S0040-5957(16)31137-4
doi: 10.2515/therapie/2015042
pii:
doi:

Types de publication

English Abstract Journal Article

Langues

fre

Sous-ensembles de citation

IM

Pagination

S11-S18

Informations de copyright

Copyright © 2016. Published by Elsevier Masson SAS.

Auteurs

Catherine Cornu (C)

Inserm, CIC1407, hôpital Louis-Pradel, CHU de Lyon, 28, avenue du Doyen-Lépine, 69500 Bron, France; Service de pharmacologie clinique et essais thérapeutiques, CHU de Lyon, 69500 Bron, France; UMR 5558, université de Lyon, 69000 Lyon, France. Electronic address: catherine.cornu@chu-lyon.fr.

Anne Donche (A)

Service de pharmacologie clinique et essais thérapeutiques, CHU de Lyon, 69500 Bron, France.

Carine Coffre (C)

Inserm, CIC 1415, CHRU de Tours, 37044 Tours, France.

Amélie Le Gouge (A)

Inserm, CIC 1415, CHRU de Tours, 37044 Tours, France.

Boulkedid Rym (B)

Unité d'épidémiologie clinique, hôpital Robert-Debré, AP-HP, 75019 Paris, France; Inserm, U 1123 et CIC 1426, hôpital Robert-Debré, 75019 Paris, France.

Isabelle Vaugier (I)

Inserm CIC 1429, hôpital Raymond-Poincaré, AP-HP, 92380 Garches, France.

Frédéric Barbot (F)

Inserm CIC 1429, hôpital Raymond-Poincaré, AP-HP, 92380 Garches, France.

Alain Leizorovicz (A)

Service de pharmacologie clinique et essais thérapeutiques, CHU de Lyon, 69500 Bron, France; UMR 5558, université de Lyon, 69000 Lyon, France.

Nadine Juge (N)

Inserm, CIC 1433, CIC-EC, 54000 Nancy, France; Pôle S2R, épidémiologie et évaluation cliniques, CHU de Nancy, 54000 Nancy, France.

Céline Giraud (C)

Inserm, CIC1407, hôpital Louis-Pradel, CHU de Lyon, 28, avenue du Doyen-Lépine, 69500 Bron, France.

François Gueyffier (F)

Service de pharmacologie clinique et essais thérapeutiques, CHU de Lyon, 69500 Bron, France; UMR 5558, université de Lyon, 69000 Lyon, France.

Alexandra Félin (A)

Inserm, CIC 1432, module épidémiologie clinique, 21079 Dijon, France; Centre d'investigation clinique, module épidémiologie clinique/essais cliniques, CHU de Dijon, 21079 Dijon, France.

Thibault Mura (T)

Centre d'investigation clinique, CHU de Montpellier, 34295 Montpellier cedex 5, France; Inserm, CIC 1411, 34295 Montpellier cedex 5, France.

Hugues Chevassus (H)

Centre d'investigation clinique, CHU de Montpellier, 34295 Montpellier cedex 5, France; Inserm, CIC 1411, 34295 Montpellier cedex 5, France.

Christine Binquet (C)

Inserm, CIC 1432, module épidémiologie clinique, 21079 Dijon, France; Centre d'investigation clinique, module épidémiologie clinique/essais cliniques, CHU de Dijon, 21079 Dijon, France.

Classifications MeSH