Modelling efforts needed to advance herpes simplex virus (HSV) vaccine development: Key findings from the World Health Organization Consultation on HSV Vaccine Impact Modelling.
HSV vaccines
Herpes simplex virus
Modelling
Sexually transmitted infections
Journal
Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899
Informations de publication
Date de publication:
28 11 2019
28 11 2019
Historique:
received:
09
12
2016
revised:
09
03
2017
accepted:
23
03
2017
pubmed:
26
6
2017
medline:
30
9
2020
entrez:
26
6
2017
Statut:
ppublish
Résumé
Development of a vaccine against herpes simplex virus (HSV) is an important goal for global sexual and reproductive health. In order to more precisely define the health and economic burden of HSV infection and the theoretical impact and cost-effectiveness of an HSV vaccine, in 2015 the World Health Organization convened an expert consultation meeting on HSV vaccine impact modelling. The experts reviewed existing model-based estimates and dynamic models of HSV infection to outline critical future modelling needs to inform development of a comprehensive business case and preferred product characteristics for an HSV vaccine. This article summarizes key findings and discussions from the meeting on modelling needs related to HSV burden, costs, and vaccine impact, essential data needs to carry out those models, and important model components and parameters.
Identifiants
pubmed: 28647165
pii: S0264-410X(17)30408-5
doi: 10.1016/j.vaccine.2017.03.074
pmc: PMC10599163
mid: NIHMS1935541
pii:
doi:
Substances chimiques
Herpes Simplex Virus Vaccines
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
7336-7345Subventions
Organisme : World Health Organization
ID : 001
Pays : International
Organisme : Medical Research Council
ID : MR/R015600/1
Pays : United Kingdom
Organisme : NIAID NIH HHS
ID : P01 AI030731
Pays : United States
Informations de copyright
Copyright © 2017. Published by Elsevier Ltd.
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