Early risk stratification using Rubidium-82 positron emission tomography in STEMI patients.
Positron emission tomography
Rubidium-82
ST-segment elevation myocardial infarction
cardiac magnetic resonance
final infarct size
myocardial blood flow
Journal
Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
ISSN: 1532-6551
Titre abrégé: J Nucl Cardiol
Pays: United States
ID NLM: 9423534
Informations de publication
Date de publication:
04 2019
04 2019
Historique:
received:
24
02
2017
accepted:
30
06
2017
pubmed:
19
7
2017
medline:
20
8
2020
entrez:
19
7
2017
Statut:
ppublish
Résumé
Assessment of infarct size after myocardial infarction is predictive of subsequent morphological changes and clinical outcome. This study aimed to assess subacute post-intervention Rubidium-82 ( STEMI patients undergoing percutaneous coronary intervention were included prospectively. Rest-only 42 patients were included, but only 35 had follow-up CMR and constituted the study population. Absolute blood flow was significantly lower in the infarct-related territory compared to remote myocardium, P < .005. Extent of hypoperfusion correlated with final infarct size, r = 0.58, P < .001, while blood flow correlated with ejection fraction, r = 0.41, P < .05. In linear mixed models, higher subacute absolute blood flow (β = 4.6, confidence interval [3.5; 5.2], P < .001, R Subacute rest-only
Sections du résumé
BACKGROUND
Assessment of infarct size after myocardial infarction is predictive of subsequent morphological changes and clinical outcome. This study aimed to assess subacute post-intervention Rubidium-82 (
METHODS
STEMI patients undergoing percutaneous coronary intervention were included prospectively. Rest-only
RESULTS
42 patients were included, but only 35 had follow-up CMR and constituted the study population. Absolute blood flow was significantly lower in the infarct-related territory compared to remote myocardium, P < .005. Extent of hypoperfusion correlated with final infarct size, r = 0.58, P < .001, while blood flow correlated with ejection fraction, r = 0.41, P < .05. In linear mixed models, higher subacute absolute blood flow (β = 4.6, confidence interval [3.5; 5.2], P < .001, R
CONCLUSIONS
Subacute rest-only
Identifiants
pubmed: 28718077
doi: 10.1007/s12350-017-0993-x
pii: 10.1007/s12350-017-0993-x
pmc: PMC6430746
doi:
Substances chimiques
Contrast Media
0
Rubidium Radioisotopes
0
Rubidium-82
9K730EL8KU
Gadolinium
AU0V1LM3JT
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
471-482Commentaires et corrections
Type : CommentIn
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