MicroRNAs in Atrial Fibrillation.

Animals Atrial Fibrillation / diagnosis Atrial Remodeling Biomarkers / analysis Gene Expression Regulation Heart Atria / metabolism Humans MicroRNAs / analysis
atrial fibrillation biomarkers cardiovascular disease miRNAs remodelling small non-coding RNA.

Journal

Current medicinal chemistry
ISSN: 1875-533X
Titre abrégé: Curr Med Chem
Pays: United Arab Emirates
ID NLM: 9440157

Informations de publication

Date de publication:
2019
Historique:
received: 10 10 2016
revised: 20 11 2016
accepted: 29 11 2016
pubmed: 22 9 2017
medline: 18 5 2019
entrez: 22 9 2017
Statut: ppublish

Résumé

MicroRNAs (miRNAs) are small non-coding RNAs, involved in regulation of post-transcriptional gene expression. They exert key role not only in physiology and normal development of the cardiovascular system but also in cardiovascular disease development and progression. Recent animal and human studies of tissue specific miRNAs have suggested a role in structural and electrical remodeling in atrial fibrillation (AF). Their emerging role as biomarkers and potential therapeutic targets in patients with AF is discussed in this review.

Identifiants

DOI: 10.2174/0929867324666170920151024 PMID: 28933293
pubmed: 28933293
pii: CMC-EPUB-85906
doi: 10.2174/0929867324666170920151024
doi:

Substances chimiques

Biomarkers 0
MicroRNAs 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

855-863

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Alexandros Briasoulis (A)

Wayne State University, Division of Cardiology, Detroit, Michigan, MI, United States.

Shikha Sharma (S)

University of Michigan, Division of Cardiology, Arrhythmia services, Ann Arbor, Michigan, MI, United States.

Tesfaye Telila (T)

Wayne State University, Division of Cardiology, Detroit, Michigan, MI, United States.

Sagar Mallikethi-Reddy (S)

Wayne State University, Division of Cardiology, Detroit, Michigan, MI, United States.

Nikolaos Papageorgiou (N)

1st Department of Cardiology, University of Athens Medical School, Athens, Greece.

Evangelos Oikonomou (E)

1st Department of Cardiology, University of Athens Medical School, Athens, Greece.

Dimitris Tousoulis (D)

1st Department of Cardiology, University of Athens Medical School, Athens, Greece.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › MicroRNAs in Atrial Fibrillation.
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Troubles du rythme cardiaque › Fibrillation auriculaire › MicroRNAs in Atrial Fibrillation.
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Fonction auriculaire › Remodelage auriculaire › MicroRNAs in Atrial Fibrillation.
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › MicroRNAs in Atrial Fibrillation.
questionsmedicales.fr › Phénomènes génétiques › Régulation de l'expression des gènes › MicroRNAs in Atrial Fibrillation.
questionsmedicales.fr › Système cardiovasculaire › Coeur › Atrium du coeur › MicroRNAs in Atrial Fibrillation.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › MicroRNAs in Atrial Fibrillation.
questionsmedicales.fr › Acides nucléiques, nucléotides et nucléosides › Acides nucléiques › ARN › ARN non traduit › Petit ARN non traduit › microARN › MicroRNAs in Atrial Fibrillation.