Effects of Coenzyme Q10 Supplementation on Serum Values of Gamma-glutamyl transferase, Pseudocholinesterase, Bilirubin, Ferritin, and High-Sensitivity C-Reactive Protein in Women with Type 2 Diabetes.
Adult
Bilirubin
/ blood
Blood Glucose
/ drug effects
Butyrylcholinesterase
/ blood
C-Reactive Protein
/ drug effects
Cholesterol, HDL
/ blood
Cholesterol, LDL
/ blood
Diabetes Mellitus, Type 2
/ blood
Dietary Supplements
Female
Ferritins
/ blood
Humans
Middle Aged
Treatment Outcome
Ubiquinone
/ administration & dosage
gamma-Glutamyltransferase
/ blood
Journal
Experimental and clinical endocrinology & diabetes : official journal, German Society of Endocrinology [and] German Diabetes Association
ISSN: 1439-3646
Titre abrégé: Exp Clin Endocrinol Diabetes
Pays: Germany
ID NLM: 9505926
Informations de publication
Date de publication:
May 2019
May 2019
Historique:
pubmed:
25
1
2018
medline:
3
9
2019
entrez:
25
1
2018
Statut:
ppublish
Résumé
Type 2 diabetes mellitus (T2DM) is a disease associated with increased oxidative stress which results from mitochondrial dysfunction. Coenzyme Q Eighty women with T2DM enrolled in this study. Thirty six of them were randomized in the drug group (receiving 100 mg/day of CoQ Serum values of FBS (P=0.039), HOMA-IR (P=0.01), ferritin (P<0.001), total cholesterol (TC) (P=0.006), LDL-C (P=0.007) decreased and HDL-C (P=0.02) increased significantly in the drug group after intervention. Serum levels of triglyceride (P=0.09) decreased marginally in CoQ The results of the current study had shown that after supplementation with 100 mg/day of CoQ
Sections du résumé
BACKGROUND
BACKGROUND
Type 2 diabetes mellitus (T2DM) is a disease associated with increased oxidative stress which results from mitochondrial dysfunction. Coenzyme Q
MATERIAL & METHODS
METHODS
Eighty women with T2DM enrolled in this study. Thirty six of them were randomized in the drug group (receiving 100 mg/day of CoQ
RESULTS
RESULTS
Serum values of FBS (P=0.039), HOMA-IR (P=0.01), ferritin (P<0.001), total cholesterol (TC) (P=0.006), LDL-C (P=0.007) decreased and HDL-C (P=0.02) increased significantly in the drug group after intervention. Serum levels of triglyceride (P=0.09) decreased marginally in CoQ
CONCLUSIONS
CONCLUSIONS
The results of the current study had shown that after supplementation with 100 mg/day of CoQ
Identifiants
pubmed: 29365333
doi: 10.1055/s-0043-124183
doi:
Substances chimiques
Blood Glucose
0
Cholesterol, HDL
0
Cholesterol, LDL
0
Ubiquinone
1339-63-5
C-Reactive Protein
9007-41-4
Ferritins
9007-73-2
gamma-Glutamyltransferase
EC 2.3.2.2
Butyrylcholinesterase
EC 3.1.1.8
coenzyme Q10
EJ27X76M46
Bilirubin
RFM9X3LJ49
Types de publication
Journal Article
Randomized Controlled Trial
Langues
eng
Sous-ensembles de citation
IM
Pagination
311-319Informations de copyright
© Georg Thieme Verlag KG Stuttgart · New York.
Déclaration de conflit d'intérêts
The authors have no conflicts of interest to declare.