A new phenanthrene dimer from Dendrobium palpebrae.

Animals Dendrobium / chemistry Free Radical Scavengers / chemistry Mice Phenanthrenes / chemistry RAW 264.7 Cells Reactive Oxygen Species / metabolism
None Orchidaceae antioxidant dendroflorin phenanthrene dimer

Journal

Journal of Asian natural products research
ISSN: 1477-2213
Titre abrégé: J Asian Nat Prod Res
Pays: England
ID NLM: 100888334

Informations de publication

Date de publication:
Apr 2019
Historique:
pubmed: 26 1 2018
medline: 4 9 2019
entrez: 26 1 2018
Statut: ppublish

Résumé

A new phenanthrene dimer, namely dendropalpebrone (1), was isolated from the whole plant of Dendrobium palpebre, along with nine known compounds (2-10). All of the isolates were evaluated for their hydroxyl radical scavenging effects using a deoxyribose assay. Dendroflorin (10) showed an appreciable activity, and therefore was selected for further studied in RAW264.7 cells. Compound 10 significantly decreased ROS in H

Identifiants

DOI: 10.1080/10286020.2018.1429416 PMID: 29368951
pubmed: 29368951
doi: 10.1080/10286020.2018.1429416
doi:

Substances chimiques

Free Radical Scavengers 0
Phenanthrenes 0
Reactive Oxygen Species 0

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

391-397

Auteurs

Napat Kyokong (N)

a Faculty of Pharmaceutical Sciences, Department of Pharmacognosy and Pharmaceutical Botany , Chulalongkorn University , Bangkok 10330 , Thailand.

Chawanphat Muangnoi (C)

b Pharmaceutical Chemistry and Natural Products Program, Faculty of Pharmaceutical Sciences , Chulalongkorn University , Bangkok 10330 , Thailand.
c Natural Products for Ageing and Chronic Diseases Research Unit, Faculty of Pharmaceutical Sciences , Chulalongkorn University , Bangkok 10330 , Thailand.

Wuttinont Thaweesest (W)

b Pharmaceutical Chemistry and Natural Products Program, Faculty of Pharmaceutical Sciences , Chulalongkorn University , Bangkok 10330 , Thailand.
c Natural Products for Ageing and Chronic Diseases Research Unit, Faculty of Pharmaceutical Sciences , Chulalongkorn University , Bangkok 10330 , Thailand.

Virunh Kongkatitham (V)

a Faculty of Pharmaceutical Sciences, Department of Pharmacognosy and Pharmaceutical Botany , Chulalongkorn University , Bangkok 10330 , Thailand.

Kittisak Likhitwitayawuid (K)

a Faculty of Pharmaceutical Sciences, Department of Pharmacognosy and Pharmaceutical Botany , Chulalongkorn University , Bangkok 10330 , Thailand.

Pornchai Rojsitthisak (P)

c Natural Products for Ageing and Chronic Diseases Research Unit, Faculty of Pharmaceutical Sciences , Chulalongkorn University , Bangkok 10330 , Thailand.
d Faculty of Pharmaceutical Sciences, Department of Food and Pharmaceutical Chemistry , Chulalongkorn University , Bangkok 10330 , Thailand.

Boonchoo Sritularak (B)

a Faculty of Pharmaceutical Sciences, Department of Pharmacognosy and Pharmaceutical Botany , Chulalongkorn University , Bangkok 10330 , Thailand.
c Natural Products for Ageing and Chronic Diseases Research Unit, Faculty of Pharmaceutical Sciences , Chulalongkorn University , Bangkok 10330 , Thailand.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › A new phenanthrene dimer from Dendrobium palpebrae.
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Lilianae › Asparagales › Orchidaceae › Dendrobium › A new phenanthrene dimer from Dendrobium palpebrae.
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Mécanismes moléculaires de l'action pharmacologique › Piégeurs de radicaux libres › A new phenanthrene dimer from Dendrobium palpebrae.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › A new phenanthrene dimer from Dendrobium palpebrae.
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Phénanthrènes › A new phenanthrene dimer from Dendrobium palpebrae.
questionsmedicales.fr › Cellules › Cellules RAW 264.7 › A new phenanthrene dimer from Dendrobium palpebrae.
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Espèces réactives de l'oxygène › A new phenanthrene dimer from Dendrobium palpebrae.