Critical Roles of Carbon Monoxide and Nitric Oxide in Ca

Animals Calcium / metabolism Calcium Signaling Carbon Monoxide / metabolism Cells, Cultured Insulin / metabolism Islets of Langerhans / metabolism Male Mice Mice, Inbred BALB C Mice, Inbred ICR Mice, Knockout Mice, Obese Nitric Oxide / metabolism
Ca carbon monoxide heme oxygenase 2 nitric oxide pancreatic β-cells

Journal

Antioxidants & redox signaling
ISSN: 1557-7716
Titre abrégé: Antioxid Redox Signal
Pays: United States
ID NLM: 100888899

Informations de publication

Date de publication:
01 02 2019
Historique:
pubmed: 1 3 2018
medline: 19 5 2020
entrez: 1 3 2018
Statut: ppublish

Résumé

Glucagon-like peptide-1 (GLP-1) increases intracellular Ca We show that NAADP-induced cGMP production by nNOS activation is dependent on carbon monoxide (CO) formation by heme oxygenase-2 (HO-2). Treatment with exogenous NO and CO amplifies cGMP formation, Ca Our research reveals the role of two gas transmitters, CO and NO, for Ca These results demonstrate that CO, the downstream regulator of NO, plays a role in bridging the gap between the Ca

Identifiants

DOI: 10.1089/ars.2017.7380 PMID: 29486595
pubmed: 29486595
doi: 10.1089/ars.2017.7380
doi:

Substances chimiques

Insulin 0
Nitric Oxide 31C4KY9ESH
Carbon Monoxide 7U1EE4V452
Calcium SY7Q814VUP

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

560-576

Auteurs

Faiz Ur Rahman (FU)

1 Department of Biochemistry, Jeonju, Republic of Korea.
2 National Creative Research Laboratory for Ca2+ Signaling Network, Chonbuk National University Medical School, Jeonju, Republic of Korea.

Dae-Ryoung Park (DR)

1 Department of Biochemistry, Jeonju, Republic of Korea.
2 National Creative Research Laboratory for Ca2+ Signaling Network, Chonbuk National University Medical School, Jeonju, Republic of Korea.

Yeonsoo Joe (Y)

2 National Creative Research Laboratory for Ca2+ Signaling Network, Chonbuk National University Medical School, Jeonju, Republic of Korea.
3 Department of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea.

Kyu Yun Jang (KY)

4 Department of Pathology Chonbuk National University Medical School, Jeonju, Republic of Korea.

Hun Taeg Chung (HT)

3 Department of Biological Sciences, University of Ulsan, Ulsan, Republic of Korea.

Uh-Hyun Kim (UH)

1 Department of Biochemistry, Jeonju, Republic of Korea.
2 National Creative Research Laboratory for Ca2+ Signaling Network, Chonbuk National University Medical School, Jeonju, Republic of Korea.
5 Institute of Cardiovascular Research, Chonbuk National University Medical School, Jeonju, Republic of Korea.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Facteurs biologiques › Facteurs de la coagulation sanguine › Calcium › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Phénomènes physiologiques cellulaires › Transduction du signal › Systèmes de seconds messagers › Signalisation calcique › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Monoxyde de carbone › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Cellules › Cellules cultivées › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Acides aminés, peptides et protéines › Peptides › Hormones peptidiques › Hormones pancréatiques › Insulines › Insuline › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Système endocrine › Glandes endocrines › Ilots pancréatiques › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée BALB C › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Lignées consanguines de souris › Souris de lignée ICR › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souris transgéniques › Souris knockout › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Rodentia › Muridae › Murinae › Souris › Souches mutantes de souris › Souris obèse › Critical Roles of Carbon Monoxide and Nitric...
questionsmedicales.fr › Produits chimiques inorganiques › Composés de l'oxygène › Oxydes › Oxydes d'azote › Monoxyde d'azote › Critical Roles of Carbon Monoxide and Nitric...