Could FDG-PET imaging play a role in the detection of progressing atherosclerosis in HIV-infected patients?


Journal

Journal of nuclear cardiology : official publication of the American Society of Nuclear Cardiology
ISSN: 1532-6551
Titre abrégé: J Nucl Cardiol
Pays: United States
ID NLM: 9423534

Informations de publication

Date de publication:
08 2019
Historique:
received: 20 02 2018
accepted: 20 02 2018
pubmed: 10 3 2018
medline: 17 3 2020
entrez: 10 3 2018
Statut: ppublish

Résumé

Important progresses in the management of patients with human immunodeficiency virus, in particular the advent of new anti-retroviral therapies (ART), have turned this rapidly fatal condition into a controllable chronic disease with a life expectancy that approaches the one from the general population. Cardiovascular diseases have now become one of the leading causes of non-HIV-related mortality in this population. Several factors including the presence of HIV in the vascular wall and the development of dyslipidemia and alteration in body fat distribution under ART might play a role the progression of atherosclerosis in HIV-infected patients. The use of imaging biomarkers may help to identify the factors associated with an increased risk of cardiovascular events and select high-risk patients who will benefit the most from the early implementation of preventive treatments.

Identifiants

pubmed: 29520571
doi: 10.1007/s12350-018-1247-2
pii: 10.1007/s12350-018-1247-2
doi:

Substances chimiques

Fluorodeoxyglucose F18 0Z5B2CJX4D

Types de publication

Editorial Comment

Langues

eng

Sous-ensembles de citation

IM

Pagination

1266-1268

Commentaires et corrections

Type : CommentOn

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Auteurs

Nidaa Mikail (N)

Department of Nuclear Medicine, Centre Hospitalier Universitaire Bichat, Assistance Publique - Hôpitaux de Paris, Département Hospitalo-Universitaire FIRE, Inserm 1148, Université Paris Diderot, Paris, France.

Mathieu Sinigaglia (M)

Department of Nuclear Medicine, Centre Hospitalier Universitaire Bichat, Assistance Publique - Hôpitaux de Paris, Département Hospitalo-Universitaire FIRE, Inserm 1148, Université Paris Diderot, Paris, France.

Fabien Hyafil (F)

Department of Nuclear Medicine, Centre Hospitalier Universitaire Bichat, Assistance Publique - Hôpitaux de Paris, Département Hospitalo-Universitaire FIRE, Inserm 1148, Université Paris Diderot, Paris, France. fabien.hyafil@aphp.fr.

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Classifications MeSH