The Hepato-protective Effects of Portulaca oleracea L. extract: Review.
Portulaca oleracea L.
antioxidant
hepatotoxic agents
hepatotoxicity
liver
traditional medicine.
Journal
Current drug discovery technologies
ISSN: 1875-6220
Titre abrégé: Curr Drug Discov Technol
Pays: United Arab Emirates
ID NLM: 101157212
Informations de publication
Date de publication:
2019
2019
Historique:
received:
19
02
2018
revised:
19
03
2018
accepted:
20
03
2018
pubmed:
31
3
2018
medline:
28
8
2020
entrez:
31
3
2018
Statut:
ppublish
Résumé
Portulaca oleracea L. (Purslane) has been used in traditional medicine against hepatic injury, although its actual efficacy has not been fully understood. The present study aimed to critically review the recent literature data from 1990 to 2017 regarding the hepato-protective effects of Portulaca oleracea L. and its underlying mechanisms. Online literature resources were checked using different search engines such as Medline, PubMed, Iran Medex, Scopus, and Google Scholar to identify articles, editorials, and reviews about antidotal effects of Portulaca oleracea L. against hepatotoxic agents. Few studies have indicated that Portulaca oleracea L. shows protective effects against hepatotoxic agents. However, due to lack of information in humans, more studies are needed to confirm the efficacy of Portulaca oleracea L. as a hepato-protective agent. The study found that Portulaca oleracea L. may be effective on hepatotoxicity by modulating oxidative stress and inflammation.
Sections du résumé
BACKGROUND
Portulaca oleracea L. (Purslane) has been used in traditional medicine against hepatic injury, although its actual efficacy has not been fully understood. The present study aimed to critically review the recent literature data from 1990 to 2017 regarding the hepato-protective effects of Portulaca oleracea L. and its underlying mechanisms.
METHODS
Online literature resources were checked using different search engines such as Medline, PubMed, Iran Medex, Scopus, and Google Scholar to identify articles, editorials, and reviews about antidotal effects of Portulaca oleracea L. against hepatotoxic agents.
RESULTS
Few studies have indicated that Portulaca oleracea L. shows protective effects against hepatotoxic agents. However, due to lack of information in humans, more studies are needed to confirm the efficacy of Portulaca oleracea L. as a hepato-protective agent.
CONCLUSION
The study found that Portulaca oleracea L. may be effective on hepatotoxicity by modulating oxidative stress and inflammation.
Identifiants
pubmed: 29600768
pii: CDDT-EPUB-89425
doi: 10.2174/1570163815666180330142724
doi:
Substances chimiques
Plant Extracts
0
Protective Agents
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
122-126Informations de copyright
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