Calibrated fMRI for mapping absolute CMRO


Journal

NeuroImage
ISSN: 1095-9572
Titre abrégé: Neuroimage
Pays: United States
ID NLM: 9215515

Informations de publication

Date de publication:
15 02 2019
Historique:
received: 02 10 2017
revised: 14 03 2018
accepted: 28 03 2018
pubmed: 2 4 2018
medline: 12 7 2019
entrez: 2 4 2018
Statut: ppublish

Résumé

Functional magnetic resonance imaging (fMRI) is an essential workhorse of modern neuroscience, providing valuable insight into the functional organisation of the brain. The physiological mechanisms underlying the blood oxygenation level dependent (BOLD) effect are complex and preclude a straightforward interpretation of the signal. However, by employing appropriate calibration of the BOLD signal, quantitative measurements can be made of important physiological parameters including the absolute rate of cerebral metabolic oxygen consumption or oxygen metabolism (CMRO

Identifiants

pubmed: 29605580
pii: S1053-8119(18)30278-7
doi: 10.1016/j.neuroimage.2018.03.068
pii:
doi:

Substances chimiques

Oxygen S88TT14065

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

145-153

Informations de copyright

Copyright © 2018 Elsevier Inc. All rights reserved.

Auteurs

M Germuska (M)

Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Maindy Road, CF24 4HQ, Cardiff, UK.

R G Wise (RG)

Cardiff University Brain Research Imaging Centre, School of Psychology, Cardiff University, Maindy Road, CF24 4HQ, Cardiff, UK. Electronic address: wiserg@cardiff.ac.uk.

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Classifications MeSH