Vaccination against the human cytomegalovirus.

Adaptive Immunity Antibodies, Neutralizing / blood Antibodies, Viral / blood Cytomegalovirus / drug effects Cytomegalovirus Infections / epidemiology Cytomegalovirus Vaccines / administration & dosage Developed Countries Developing Countries Female Humans Infant, Newborn Infectious Disease Transmission, Vertical / prevention & control Organ Transplantation / adverse effects Prevalence Vaccination / methods Vaccines, Attenuated Vaccines, Live, Unattenuated
CMV Congenital infection Deafness Pentamer Reinfection

Journal

Vaccine
ISSN: 1873-2518
Titre abrégé: Vaccine
Pays: Netherlands
ID NLM: 8406899

Informations de publication

Date de publication:
28 11 2019
Historique:
received: 11 02 2018
accepted: 19 02 2018
pubmed: 7 4 2018
medline: 23 7 2020
entrez: 7 4 2018
Statut: ppublish

Résumé

The human cytomegalovirus (HCMV) is the most important infectious cause of congenital abnormalities and also of infectious complications of transplantation. The biology of the infection is complex and acquired immunity does not always prevent reinfection. Nevertheless, vaccine development is far advanced, with numerous candidate vaccines being tested, both live and inactivated. This article summarizes the status of the candidate vaccines.

Identifiants

DOI: 10.1016/j.vaccine.2018.02.089 PMID: 29622379 PMC: PMC6892274
pubmed: 29622379
pii: S0264-410X(18)30288-3
doi: 10.1016/j.vaccine.2018.02.089
pmc: PMC6892274
pii:
doi:

Substances chimiques

Antibodies, Neutralizing 0
Antibodies, Viral 0
Cytomegalovirus Vaccines 0
Vaccines, Attenuated 0
Vaccines, Live, Unattenuated 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

7437-7442

Informations de copyright

Copyright © 2018. Published by Elsevier Ltd.

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Auteurs

Stanley A Plotkin (SA)

University of Pennsylvania, Vaxconsult, 4650 Wismer Rd., Doylestown, PA 18902, United States. Electronic address: Stanley.plotkin@vaxconsult.com.

Suresh B Boppana (SB)

UAB School of Medicine, CHB 114, 1600 7th Avenue South, Birmingham, AL 35233, United States. Electronic address: sboppana@peds.uab.edu.

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Classifications MeSH

questionsmedicales.fr › Phénomènes du système immunitaire › Immunité › Immunité acquise › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps neutralisants › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Globulines › Sérum-globulines › Immunoglobulines › Anticorps › Anticorps antiviraux › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Virus › Virus à ADN › Herpesviridae › Betaherpesvirinae › Cytomegalovirus › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Infection › Maladies virales › Infections à virus à ADN › Infections à Herpesviridae › Infections à cytomégalovirus › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins antiviraux › Vaccins contre le cytomégalovirus › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Sciences sociales › Internationalité › Coopération internationale › Pays développés › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Sciences sociales › Internationalité › Coopération internationale › Pays en voie de développement › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Personnes › Tranches d'âge › Nourrisson › Nouveau-né › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Transmission de maladie infectieuse › Transmission verticale de maladie infectieuse › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Procédures de chirurgie opératoire › Transplantation › Transplantation d'organe › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Collecte de données › Registre civil › Morbidité › Prévalence › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Environnement et santé publique › Santé publique › Pratiques en santé publique › Prévention primaire › Immunisation › Vaccination › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins atténués › Vaccination against the human cytomegalovirus.
questionsmedicales.fr › Mélanges complexes › Produits biologiques › Vaccins › Vaccins vivants non atténués › Vaccination against the human cytomegalovirus.