Elevated post-void residual volume in a geriatric post-hip fracture assessment in women-associated factors and risk of mortality.


Journal

Aging clinical and experimental research
ISSN: 1720-8319
Titre abrégé: Aging Clin Exp Res
Pays: Germany
ID NLM: 101132995

Informations de publication

Date de publication:
Jan 2019
Historique:
received: 02 01 2018
accepted: 05 04 2018
pubmed: 11 4 2018
medline: 14 3 2019
entrez: 11 4 2018
Statut: ppublish

Résumé

Multiple factors contribute to elevated post-void residual urine volumes (PVR), but they may indicate detrusor underactivity (DU), especially in older women. The aim here was to examine factors associated with and prognostic significance of elevated PVR in a geriatric post-hip fracture assessment in a female population. Consecutive female hip fracture patients (n = 409) aged 65 years and older were included. PVR was measured by bladder scanner. PVR of 160 ml or more was deemed elevated. Age-adjusted univariate logistic regression analyses were conducted to examine the association of the domains of the comprehensive geriatric assessment (CGA) with elevated PVR. Cox proportional hazards model was used to determine the age-adjusted association of an elevated PVR with 1-year mortality. Of the patients, 64 (15.6%) had elevated PVR. Having urinary or fecal incontinence, difficulties in physical activities of daily living, malnutrition, poor performance on Timed Up and Go and Elderly Mobility Scale were significantly associated with elevated PVR. Difficulties in instrumental activities of daily living, renal dysfunction, constipation, polypharmacy, nocturia, cognitive impairment and depressive mood were not associated with elevated PVR. Elevated PVR significantly increased the risk of mortality 1 year post hip fracture. Elevated PVR is relatively common in older female hip fracture patients and associated with physical functioning, malnutrition and risk of mortality. Even though a causal relationship cannot be confirmed, the findings may suggest a relationship between DU and physical frailty. PVR deserves to be included in the CGA of frail older patients including women.

Sections du résumé

BACKGROUND AND AIM OBJECTIVE
Multiple factors contribute to elevated post-void residual urine volumes (PVR), but they may indicate detrusor underactivity (DU), especially in older women. The aim here was to examine factors associated with and prognostic significance of elevated PVR in a geriatric post-hip fracture assessment in a female population.
METHODS METHODS
Consecutive female hip fracture patients (n = 409) aged 65 years and older were included. PVR was measured by bladder scanner. PVR of 160 ml or more was deemed elevated. Age-adjusted univariate logistic regression analyses were conducted to examine the association of the domains of the comprehensive geriatric assessment (CGA) with elevated PVR. Cox proportional hazards model was used to determine the age-adjusted association of an elevated PVR with 1-year mortality.
RESULTS RESULTS
Of the patients, 64 (15.6%) had elevated PVR. Having urinary or fecal incontinence, difficulties in physical activities of daily living, malnutrition, poor performance on Timed Up and Go and Elderly Mobility Scale were significantly associated with elevated PVR. Difficulties in instrumental activities of daily living, renal dysfunction, constipation, polypharmacy, nocturia, cognitive impairment and depressive mood were not associated with elevated PVR. Elevated PVR significantly increased the risk of mortality 1 year post hip fracture.
CONCLUSIONS CONCLUSIONS
Elevated PVR is relatively common in older female hip fracture patients and associated with physical functioning, malnutrition and risk of mortality. Even though a causal relationship cannot be confirmed, the findings may suggest a relationship between DU and physical frailty. PVR deserves to be included in the CGA of frail older patients including women.

Identifiants

pubmed: 29633169
doi: 10.1007/s40520-018-0946-5
pii: 10.1007/s40520-018-0946-5
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

75-83

Subventions

Organisme : State Research Financing of Seinäjoki Central Hospital
ID : 5600/3212
Organisme : Research Fund of Hospital District of Southern Ostrobothnia
ID : 5100/2125

Auteurs

Maria S Nuotio (MS)

Department of Geriatric Medicine, Seinäjoki Central Hospital, Hanneksenrinne 7, 60220, Seinäjoki, Finland. maria.nuotio@fimnet.fi.

Tiina Luukkaala (T)

Science Center, Pirkanmaa Hospital District, Tampere, Finland.
School of Health Sciences, University of Tampere, Tampere, Finland.

Teuvo Tammela (T)

Department of Surgery, Faculty of Medicine and Life Sciences, University of Tampere, Tampere, Finland.
Tampere University Hospital, Tampere, Finland.

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Classifications MeSH