Lipid Testing and Statin Prescriptions Among Medicaid Recipients With Systemic Lupus Erythematosus or Diabetes Mellitus and the General Medicaid Population.
Adolescent
Adult
Aged
Cohort Studies
Diabetes Mellitus
/ blood
Drug Prescriptions
Female
Follow-Up Studies
Hematologic Tests
/ trends
Humans
Hydroxymethylglutaryl-CoA Reductase Inhibitors
/ adverse effects
Lipids
/ blood
Lupus Erythematosus, Systemic
/ blood
Male
Medicaid
/ trends
Middle Aged
Population Surveillance
United States
/ epidemiology
Young Adult
Journal
Arthritis care & research
ISSN: 2151-4658
Titre abrégé: Arthritis Care Res (Hoboken)
Pays: United States
ID NLM: 101518086
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
19
09
2007
accepted:
03
04
2018
pubmed:
13
4
2018
medline:
15
10
2019
entrez:
13
4
2018
Statut:
ppublish
Résumé
Cardiovascular disease (CVD) risks in systemic lupus erythematosus (SLE) are similar to those in diabetes mellitus (DM). We investigated whether the numbers of lipid tests and statin prescriptions in patients with SLE are comparable with those in patients with DM and those in individuals without either disease. Using Analytic eXtract files from 29 states for 2007-2010, we identified a cohort of US Medicaid beneficiaries, ages 18-65 years, with prevalent SLE. Each SLE patient was matched for age and sex with 2 patients with DM and 4 individuals in the general Medicaid population who did not have either SLE or DM. We compared the proportions of patients in each cohort who received ≥1 lipid test and ≥1 statin prescription during 1-year follow-up. We used multivariable logistic regression to calculate the odds of lipid testing and receiving prescriptions for statins and conditional logistic regression to compare the matched cohorts. We identified 3 Medicaid cohorts: 25,950 patients with SLE, 51,900 patients with DM, and 103,800 Medicaid recipients without either condition. In these cohorts, lipid testing was performed in 24% of patients in the SLE group, 43% of patients in the DM group, and 16% of individuals in the group with neither condition, and statin prescriptions were dispensed in 11%, 33%, and 7% of these groups, respectively. SLE patients were 66% less likely (odds ratio [OR] 0.34, 95% confidence interval [95% CI] 0.34-0.35) to have lipid tests and 82% less likely (OR 0.18, 95% CI 0.18-0.18) to fill a statin prescription compared with DM patients. SLE patients were also less likely (OR 0.89, 95% CI 0.84-0.94) to fill a statin prescription compared with individuals in the general Medicaid population. Despite having an elevated risk of CVD, SLE patients received less lipid testing and received fewer statin prescriptions compared with age- and sex-matched DM patients and individuals in the general Medicaid population; this gap should be a target for improvement.
Identifiants
pubmed: 29648687
doi: 10.1002/acr.23574
pmc: PMC6185821
mid: NIHMS957611
doi:
Substances chimiques
Hydroxymethylglutaryl-CoA Reductase Inhibitors
0
Lipids
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
104-115Subventions
Organisme : Biogen-Idec
Pays : International
Organisme : NIAMS NIH HHS
ID : R01 AR057327
Pays : United States
Organisme : NIAMS NIH HHS
ID : K24 AR066109
Pays : United States
Organisme : Rheumatology Research Foundation
Pays : International
Organisme : Lupus Foundation of America
Pays : International
Organisme : Merck
Pays : International
Organisme : Pfizer
Pays : International
Organisme : GlaxoSmithKline
Pays : International
Organisme : NIAMS NIH HHS
ID : K23 AR071500
Pays : United States
Informations de copyright
© 2018, American College of Rheumatology.
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