Association between fat mass, adipose tissue, fat fraction per adipose tissue, and metabolic risks: a cross-sectional study in normal, overweight, and obese adults.
Adipose Tissue
/ diagnostic imaging
Adolescent
Adult
Body Fat Distribution
/ methods
Calorimetry, Indirect
/ methods
Cross-Sectional Studies
Female
Humans
Magnetic Resonance Imaging
/ methods
Male
Metabolic Diseases
/ etiology
Middle Aged
Multivariate Analysis
Obesity
/ complications
Observer Variation
Overweight
/ complications
Regression Analysis
Reproducibility of Results
Risk Assessment
/ methods
Whole Body Imaging
/ methods
Young Adult
Journal
European journal of clinical nutrition
ISSN: 1476-5640
Titre abrégé: Eur J Clin Nutr
Pays: England
ID NLM: 8804070
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
07
11
2017
accepted:
15
02
2018
revised:
19
01
2018
pubmed:
20
4
2018
medline:
7
9
2019
entrez:
20
4
2018
Statut:
ppublish
Résumé
We investigated whether fat mass (FM) and total adipose tissue (TAT) can be used interchangeably and FM per TAT adds to metabolic risk assessment. Cross-sectional data were assessed in 377 adults (aged 18-60 years; 51.2% women). FM was measured by either 4-compartment (4C) model or quantitative magnetic resonance (QMR); total-, subcutaneous- and visceral adipose tissue (TAT, SAT, VAT), and liver fat by whole-body MRI; leptin, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), C-reactive protein (CRP), and triglycerides; resting energy expenditure and respiratory quotient by indirect calorimetry were determined. Correlations and stepwise multivariate regression analyses were performed. FM Independent of FM or TAT, FM
Sections du résumé
BACKGROUND/OBJECTIVES
We investigated whether fat mass (FM) and total adipose tissue (TAT) can be used interchangeably and FM per TAT adds to metabolic risk assessment.
SUBJECTS/METHODS
Cross-sectional data were assessed in 377 adults (aged 18-60 years; 51.2% women). FM was measured by either 4-compartment (4C) model or quantitative magnetic resonance (QMR); total-, subcutaneous- and visceral adipose tissue (TAT, SAT, VAT), and liver fat by whole-body MRI; leptin, insulin, homeostasis model assessment of insulin resistance (HOMA-IR), C-reactive protein (CRP), and triglycerides; resting energy expenditure and respiratory quotient by indirect calorimetry were determined. Correlations and stepwise multivariate regression analyses were performed.
RESULTS
FM
CONCLUSIONS
Independent of FM or TAT, FM
Identifiants
pubmed: 29670259
doi: 10.1038/s41430-018-0150-x
pii: 10.1038/s41430-018-0150-x
doi:
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM