Biomaterial granules used for filling bone defects constitute 3D scaffolds: porosity, microarchitecture and molecular composition analyzed by microCT and Raman microspectroscopy.


Journal

Journal of biomedical materials research. Part B, Applied biomaterials
ISSN: 1552-4981
Titre abrégé: J Biomed Mater Res B Appl Biomater
Pays: United States
ID NLM: 101234238

Informations de publication

Date de publication:
02 2019
Historique:
received: 07 02 2018
accepted: 23 03 2018
pubmed: 21 4 2018
medline: 17 6 2020
entrez: 21 4 2018
Statut: ppublish

Résumé

Biomaterials are used in the granular form to fill small bone defects. Granules can be prepared with a grinder from trabecular bone samples or provided as synthetic biomaterials by industry. Granules occupy the 3D-space and create a macroporosity allowing invasion of vascular and bone cells when the inter-granular pores are larger than 300 µm. We compared the 3D-porosity of granule stacks obtained or prepared with nine biomaterials Osteopure

Identifiants

pubmed: 29675998
doi: 10.1002/jbm.b.34133
doi:

Substances chimiques

Bio-Oss 0
Calcium Phosphates 0
Lubboc 0
Minerals 0

Types de publication

Comparative Study Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

415-423

Informations de copyright

© 2018 Wiley Periodicals, Inc.

Auteurs

Baptiste Arbez (B)

Groupe Etudes Remodelage Osseux et bioMatériaux, GEROM - LabCom NextBone, SFR 42-08, Université d'Angers, IRIS-IBS Institut de Biologie en Santé, CHU d'Angers, 49933, Angers Cedex, France.

Jean-Daniel Kün-Darbois (JD)

Groupe Etudes Remodelage Osseux et bioMatériaux, GEROM - LabCom NextBone, SFR 42-08, Université d'Angers, IRIS-IBS Institut de Biologie en Santé, CHU d'Angers, 49933, Angers Cedex, France.
Service de chirurgie maxillo-faciale, CHU d'Angers, 49933, Angers Cedex, France.

Thierry Convert (T)

CFI, Collège Français d'Implantologie, 6 rue de Rome, 75005, Paris, France.

Bernard Guillaume (B)

Groupe Etudes Remodelage Osseux et bioMatériaux, GEROM - LabCom NextBone, SFR 42-08, Université d'Angers, IRIS-IBS Institut de Biologie en Santé, CHU d'Angers, 49933, Angers Cedex, France.
CFI, Collège Français d'Implantologie, 6 rue de Rome, 75005, Paris, France.

Philippe Mercier (P)

Groupe Etudes Remodelage Osseux et bioMatériaux, GEROM - LabCom NextBone, SFR 42-08, Université d'Angers, IRIS-IBS Institut de Biologie en Santé, CHU d'Angers, 49933, Angers Cedex, France.

Laurent Hubert (L)

Groupe Etudes Remodelage Osseux et bioMatériaux, GEROM - LabCom NextBone, SFR 42-08, Université d'Angers, IRIS-IBS Institut de Biologie en Santé, CHU d'Angers, 49933, Angers Cedex, France.
Département de chirurgie osseuse, CHU d'Angers, 49933, Angers Cedex, France.

Daniel Chappard (D)

Groupe Etudes Remodelage Osseux et bioMatériaux, GEROM - LabCom NextBone, SFR 42-08, Université d'Angers, IRIS-IBS Institut de Biologie en Santé, CHU d'Angers, 49933, Angers Cedex, France.

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Classifications MeSH