Platelet-rich plasma on female androgenetic alopecia: Tested on 10 patients.
adjuvant therapy
androgenetic alopecia
hair density
platelet-rich plasma
vellus hair
Journal
Journal of cosmetic dermatology
ISSN: 1473-2165
Titre abrégé: J Cosmet Dermatol
Pays: England
ID NLM: 101130964
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
accepted:
19
03
2018
pubmed:
1
5
2018
medline:
28
5
2019
entrez:
1
5
2018
Statut:
ppublish
Résumé
Recently, platelet-rich plasma (PRP) injection has been proposed as a potential adjuvant therapy to treat androgenetic alopecia. Investigate the efficacy, tolerability, and clinical improvement of PRP for the treatment of female AGA. A total of 10 female patients affected by AGA and not responding to treatment with minoxidil and/or oral antiandrogens were enrolled. The clinical improvement was evaluated by pull test, global photographs, and Trichoscan at weeks 9, 12, and 24, and hair measurements were performed at baseline and 12 and 24 weeks after the first session. After 24 weeks, the median relative percentage change (%RC) for all the parameters of hair density was mostly positive. After 12 weeks, the medium hair diameter in frontal area showed a significant increase (%RD = 12.5, with P-value < .05), and after 24 weeks (%RD = 14.6, P-value < .05), the vellus relative change instead showed a decrease, especially in the front and the central area, while for the vertex, the decrease was mainly visible at the end (-6.6%). No adverse events were reported. Platelet-rich plasma injections have a positive therapeutic effect on hair density and hair diameter improvement.
Sections du résumé
BACKGROUND
BACKGROUND
Recently, platelet-rich plasma (PRP) injection has been proposed as a potential adjuvant therapy to treat androgenetic alopecia.
AIMS
OBJECTIVE
Investigate the efficacy, tolerability, and clinical improvement of PRP for the treatment of female AGA.
PATIENTS/METHODS
METHODS
A total of 10 female patients affected by AGA and not responding to treatment with minoxidil and/or oral antiandrogens were enrolled. The clinical improvement was evaluated by pull test, global photographs, and Trichoscan at weeks 9, 12, and 24, and hair measurements were performed at baseline and 12 and 24 weeks after the first session.
RESULTS
RESULTS
After 24 weeks, the median relative percentage change (%RC) for all the parameters of hair density was mostly positive. After 12 weeks, the medium hair diameter in frontal area showed a significant increase (%RD = 12.5, with P-value < .05), and after 24 weeks (%RD = 14.6, P-value < .05), the vellus relative change instead showed a decrease, especially in the front and the central area, while for the vertex, the decrease was mainly visible at the end (-6.6%). No adverse events were reported.
CONCLUSION
CONCLUSIONS
Platelet-rich plasma injections have a positive therapeutic effect on hair density and hair diameter improvement.
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
59-64Informations de copyright
© 2018 Wiley Periodicals, Inc.