Mechano-chronotropic Unloading During the Acute Phase of Myocardial Infarction Markedly Reduces Infarct Size via the Suppression of Myocardial Oxygen Consumption.

Animals Cardiovascular Agents / pharmacology Combined Modality Therapy Disease Models, Animal Dogs Heart Rate / drug effects Heart-Assist Devices Ivabradine / pharmacology Myocardial Infarction / metabolism Myocardium / metabolism Oxygen Consumption Prosthesis Design Prosthesis Implantation / adverse effects Recovery of Function Ventricular Function, Left
Acute myocardial infarction Impella Infarct size Ivabradine Left ventricular assist device Pressure-volume loop

Journal

Journal of cardiovascular translational research
ISSN: 1937-5395
Titre abrégé: J Cardiovasc Transl Res
Pays: United States
ID NLM: 101468585

Informations de publication

Date de publication:
04 2019
Historique:
received: 31 01 2018
accepted: 27 04 2018
pubmed: 8 5 2018
medline: 13 2 2020
entrez: 9 5 2018
Statut: ppublish

Résumé

The oxygen supply-demand imbalance is the fundamental pathophysiology of myocardial infarction (MI). Reducing myocardial oxygen consumption (MVO

Identifiants

DOI: 10.1007/s12265-018-9809-x PMID: 29736746
pubmed: 29736746
doi: 10.1007/s12265-018-9809-x
pii: 10.1007/s12265-018-9809-x
doi:

Substances chimiques

Cardiovascular Agents 0
Ivabradine 3H48L0LPZQ

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

124-134

Références

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Auteurs

Genya Sunagawa (G)

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

Keita Saku (K)

Department of Advanced Risk Stratification for Cardiovascular Diseases, Center for Disruptive Cardiovascular Medicine, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan. saku@cardiol.med.kyushu-u.ac.jp.

Takahiro Arimura (T)

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

Takuya Nishikawa (T)

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

Hiroshi Mannoji (H)

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

Kazuhiro Kamada (K)

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

Kiyokazu Abe (K)

Department of Anesthesiology & Critical Care Medicine, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

Takuya Kishi (T)

Department of Advanced Risk Stratification for Cardiovascular Diseases, Center for Disruptive Cardiovascular Medicine, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

Hiroyuki Tsutsui (H)

Department of Cardiovascular Medicine, Graduate School of Medical Sciences, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

Kenji Sunagawa (K)

Department of Therapeutic Regulation of Cardiovascular Homeostasis, Center for Disruptive Cardiovascular Medicine, Kyushu University, 3-1-1 Maidashi Higashi-ku, Fukuoka, 812-8582, Japan.

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Classifications MeSH

questionsmedicales.fr › Eucaryotes › Animaux › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Actions chimiques et utilisations › Actions pharmacologiques › Utilisations thérapeutiques › Agents cardiovasculaires › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Thérapeutique › Association thérapeutique › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Techniques d'investigation › Modèles théoriques › Modèles biologiques › Modèles animaux de maladie humaine › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Carnivora › Pinnipedia › Canidae › Chiens › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Hémodynamique › Rythme cardiaque › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Équipement et fournitures › Équipement chirurgical › Organes artificiels › Coeur artificiel › Dispositifs d'assistance circulatoire › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Composés hétérocycliques › Composés hétérocycliques à cycles fusionnés › Composés hétérobicycliques › Benzazépines › Ivabradine › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Nécrose › Infarctus › Infarctus du myocarde › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Tissus › Muscles › Muscle strié › Myocarde › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Métabolisme › Consommation d'oxygène › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Équipement et fournitures › Prothèses et implants › Conception de prothèse › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Procédures de chirurgie opératoire › Implantation de prothèse › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Phénomènes biologiques › Récupération fonctionnelle › Mechano-chronotropic Unloading During the...
questionsmedicales.fr › Phénomènes physiologiques respiratoires et circulatoires › Phénomènes physiologiques cardiovasculaires › Fonction ventriculaire › Fonction ventriculaire gauche › Mechano-chronotropic Unloading During the...