Chronic Low Back Pain: Current Pharmacotherapeutic Therapies and a New Biological Approach.
Chronic low back pain
chronic pain management
collagen-containing injections
pain control
pharmacotherapy of chronic pain
safe therapy of
pain.
Journal
Current medicinal chemistry
ISSN: 1875-533X
Titre abrégé: Curr Med Chem
Pays: United Arab Emirates
ID NLM: 9440157
Informations de publication
Date de publication:
2019
2019
Historique:
received:
25
03
2017
revised:
05
07
2017
accepted:
25
04
2018
pubmed:
15
5
2018
medline:
25
6
2019
entrez:
15
5
2018
Statut:
ppublish
Résumé
Chronic low back pain (CLBP) syndrome represents one of the leading causes of long-term disability worldwide. The prevalence of CLBP has been rising significantly in relation to increasing average life expectancy. CLBP results from chronification of acute low back pain. There are many factors contributing to the CLBP crisis; common etiopathogenetic factors include e.g., functional blockage of intervertebral joints. The treatment of CLBP is complex. An important part of treatment consists of pain pharmacotherapy, for which several groups of drugs are used. The problem lies in the side effects of many of these traditionally used medications. Therefore, new and safer treatment methods are being sought. Innovative options for CLBP pharmacology include injections containing collagen, which can be combined with other traditionally used drugs, which helps reduce dosages and increase the overall safety of CLBP therapy.
Identifiants
pubmed: 29756567
pii: CMC-EPUB-90366
doi: 10.2174/0929867325666180514102146
doi:
Substances chimiques
Analgesics
0
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
1019-1026Informations de copyright
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