The Clinical Innovation Network: a policy for promoting development of drugs and medical devices in Japan.
Journal
Drug discovery today
ISSN: 1878-5832
Titre abrégé: Drug Discov Today
Pays: England
ID NLM: 9604391
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
10
04
2018
revised:
02
05
2018
accepted:
21
05
2018
pubmed:
29
5
2018
medline:
30
7
2019
entrez:
28
5
2018
Statut:
ppublish
Résumé
The continuous increase in the costs of developing new drugs and medical devices drives increases in medical expenses. Seventy to ninety percent of these costs are associated with clinical trials. Therefore, the development of cost-effective methods to perform clinical trials remains a challenge. One approach is to use patient registries, collections of data related to patients with a specific diagnosis, condition, or procedure. Patient registries are used in Denmark, Sweden, and the USA for the enrollment of patients into clinical trials, and to evaluate endpoints. In Japan, a national project for registry-oriented clinical research, termed the 'Clinical Innovation Network' (CIN), was initiated in 2016. Here, we provide an overview of the CIN and discuss its impact on drug and device development in Japan.
Identifiants
pubmed: 29803934
pii: S1359-6446(18)30026-6
doi: 10.1016/j.drudis.2018.05.026
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Pagination
4-8Informations de copyright
Copyright © 2018 Elsevier Ltd. All rights reserved.