MARCKS phosphorylation and amylase release in GLP-1-stimulated acini isolated from rat pancreas.
Acinar Cells
/ drug effects
Amylases
/ metabolism
Animals
Exocytosis
/ drug effects
Glucagon-Like Peptide 1
/ pharmacology
Male
Myristoylated Alanine-Rich C Kinase Substrate
/ metabolism
Pancreas
/ drug effects
Phosphorylation
/ drug effects
Rats
Rats, Sprague-Dawley
Signal Transduction
/ drug effects
Amylase
Exocytosis
GLP-1
MARCKS
PKA
Journal
The journal of physiological sciences : JPS
ISSN: 1880-6562
Titre abrégé: J Physiol Sci
Pays: Japan
ID NLM: 101262417
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
25
02
2018
accepted:
23
05
2018
pubmed:
31
5
2018
medline:
30
5
2019
entrez:
31
5
2018
Statut:
ppublish
Résumé
Little is known about the effects of glucagon-like peptide 1 (GLP-1) on the pancreatic exocrine gland. In the gland, secretagogues induce amylase release. That signal transduction is evoked mainly by an increase in intracellular Ca
Identifiants
pubmed: 29845509
doi: 10.1007/s12576-018-0621-9
pii: 10.1007/s12576-018-0621-9
pmc: PMC10717726
doi:
Substances chimiques
Myristoylated Alanine-Rich C Kinase Substrate
125267-21-2
Glucagon-Like Peptide 1
89750-14-1
Amylases
EC 3.2.1.-
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
143-149Subventions
Organisme : Japan Society for the Promotion of Science
ID : 15K21322
Organisme : Japan Society for the Promotion of Science
ID : 15K11060
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