The circadian clock in adult neural stem cell maintenance.
Aging
Circadian rhythms
Metabolism
Neural stem cell
Quiescence
SIRT1
Journal
Progress in neurobiology
ISSN: 1873-5118
Titre abrégé: Prog Neurobiol
Pays: England
ID NLM: 0370121
Informations de publication
Date de publication:
02 2019
02 2019
Historique:
received:
30
01
2018
revised:
14
05
2018
accepted:
29
05
2018
pubmed:
11
6
2018
medline:
18
2
2020
entrez:
11
6
2018
Statut:
ppublish
Résumé
Neural stem cells persist in the adult central nervous system as a continuing source of astrocytes, oligodendrocytes and neurons. Various signalling pathways and transcription factors actively maintain this population by regulating cell cycle entry and exit. Similarly, the circadian clock is interconnected with the cell cycle and actively maintains stem cell populations in various tissues. Here, we discuss emerging evidence for an important role of the circadian clock in neural stem cell maintenance. We propose that the NAD
Identifiants
pubmed: 29886147
pii: S0301-0082(18)30020-0
doi: 10.1016/j.pneurobio.2018.05.007
pii:
doi:
Types de publication
Journal Article
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
41-53Informations de copyright
Copyright © 2018 Elsevier Ltd. All rights reserved.