Constitutive IP
Amino Acid Sequence
Apoptosis
/ drug effects
Calcium
/ metabolism
Cell Line, Tumor
Humans
Inositol 1,4,5-Trisphosphate Receptors
/ genetics
Lymphoma, Large B-Cell, Diffuse
/ genetics
Peptides
/ pharmacology
Proto-Oncogene Proteins c-bcl-2
/ antagonists & inhibitors
Signal Transduction
/ drug effects
Transfection
Journal
Cell death and differentiation
ISSN: 1476-5403
Titre abrégé: Cell Death Differ
Pays: England
ID NLM: 9437445
Informations de publication
Date de publication:
03 2019
03 2019
Historique:
received:
30
07
2017
accepted:
16
05
2018
revised:
15
05
2018
pubmed:
15
6
2018
medline:
4
6
2020
entrez:
15
6
2018
Statut:
ppublish
Résumé
Anti-apoptotic Bcl-2 proteins are upregulated in different cancers, including diffuse large B-cell lymphoma (DLBCL) and chronic lymphocytic leukemia (CLL), enabling survival by inhibiting pro-apoptotic Bcl-2-family members and inositol 1,4,5-trisphosphate (IP
Identifiants
pubmed: 29899382
doi: 10.1038/s41418-018-0142-3
pii: 10.1038/s41418-018-0142-3
pmc: PMC6370760
doi:
Substances chimiques
BCL2 protein, human
0
BIRD-2 peptide
0
Inositol 1,4,5-Trisphosphate Receptors
0
Peptides
0
Proto-Oncogene Proteins c-bcl-2
0
Calcium
SY7Q814VUP
Types de publication
Journal Article
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
531-547Références
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