Cystatin C as a predictor of mortality in elderly patients with chronic kidney disease.

Aged Biomarkers / blood Creatinine / blood Cystatin C / blood Female Glomerular Filtration Rate Humans Longitudinal Studies Male Predictive Value of Tests Proportional Hazards Models Renal Insufficiency, Chronic / blood
51CrEDTA clearance Serum cystatin C elderly CKD patients glomerular filtration rate estimation equations mortality

Journal

The aging male : the official journal of the International Society for the Study of the Aging Male
ISSN: 1473-0790
Titre abrégé: Aging Male
Pays: England
ID NLM: 9808210

Informations de publication

Date de publication:
Mar 2019
Historique:
pubmed: 19 6 2018
medline: 2 5 2019
entrez: 19 6 2018
Statut: ppublish

Résumé

The prevalence of chronic kidney disease (CKD) in the elderly is high. Serum cystatin C is an accurate marker of kidney function and it also has prognostic utility in CKD patients. The aim of our study was to determine the prediction of serum cystatin C and other markers of kidney function on long-term survival in elderly CKD patients. Fifty eight adult Caucasian patients, older than 65 years, without known malignancy, thyroid disease and/or not on steroid therapy were enrolled in the study. In each patient, The means are as follows: Our results showed the highest HR for serum cystatin C among kidney function markers for prediction of outcome in elderly CKD patients.

Sections du résumé

BACKGROUND BACKGROUND
The prevalence of chronic kidney disease (CKD) in the elderly is high. Serum cystatin C is an accurate marker of kidney function and it also has prognostic utility in CKD patients. The aim of our study was to determine the prediction of serum cystatin C and other markers of kidney function on long-term survival in elderly CKD patients.
METHODS METHODS
Fifty eight adult Caucasian patients, older than 65 years, without known malignancy, thyroid disease and/or not on steroid therapy were enrolled in the study. In each patient,
RESULTS RESULTS
The means are as follows:
CONCLUSIONS CONCLUSIONS
Our results showed the highest HR for serum cystatin C among kidney function markers for prediction of outcome in elderly CKD patients.

Identifiants

DOI: 10.1080/13685538.2018.1479386 PMID: 29912597
pubmed: 29912597
doi: 10.1080/13685538.2018.1479386
doi:

Substances chimiques

Biomarkers 0
Cystatin C 0
Creatinine AYI8EX34EU

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

62-67

Auteurs

Sebastjan Bevc (S)

a Department of Nephrology, Clinic for Internal Medicine , University Clinical Centre Maribor , Maribor , Slovenia.
b Faculty of Medicine , University of Maribor , Maribor , Slovenia.

Nina Hojs (N)

a Department of Nephrology, Clinic for Internal Medicine , University Clinical Centre Maribor , Maribor , Slovenia.
b Faculty of Medicine , University of Maribor , Maribor , Slovenia.

Maša Knehtl (M)

a Department of Nephrology, Clinic for Internal Medicine , University Clinical Centre Maribor , Maribor , Slovenia.
b Faculty of Medicine , University of Maribor , Maribor , Slovenia.

Robert Ekart (R)

b Faculty of Medicine , University of Maribor , Maribor , Slovenia.
c Department of Dialysis, Clinic for Internal Medicine , University Clinical Centre Maribor , Maribor , Slovenia.

Radovan Hojs (R)

a Department of Nephrology, Clinic for Internal Medicine , University Clinical Centre Maribor , Maribor , Slovenia.
b Faculty of Medicine , University of Maribor , Maribor , Slovenia.

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Classifications MeSH

questionsmedicales.fr › Personnes › Tranches d'âge › Adulte › Sujet âgé › Cystatin C as a predictor of mortality in...
questionsmedicales.fr › Facteurs biologiques › Marqueurs biologiques › Cystatin C as a predictor of mortality in...
questionsmedicales.fr › Composés hétérocycliques › Composés hétéromonocycliques › Azoles › Imidazoles › Créatinine › Cystatin C as a predictor of mortality in...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Cystatines › Cystatine C › Cystatin C as a predictor of mortality in...
questionsmedicales.fr › Phénomènes physiologiques des appareils urinaire et reproducteur › Phénomènes physiologiques des voies urinaires › Débit de filtration glomérulaire › Cystatin C as a predictor of mortality in...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Cystatin C as a predictor of mortality in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Caractéristiques des études épidémiologiques › Études épidémiologiques › Études de cohortes › Études longitudinales › Cystatin C as a predictor of mortality in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Méthodologie en recherche épidémiologique › Valeur prédictive des tests › Cystatin C as a predictor of mortality in...
questionsmedicales.fr › Environnement et santé publique › Santé publique › Méthodes épidémiologiques › Statistiques comme sujet › Analyse de survie › Modèles des risques proportionnels › Cystatin C as a predictor of mortality in...
questionsmedicales.fr › États, signes et symptômes pathologiques › Processus pathologiques › Caractéristiques de la maladie › Maladie chronique › Insuffisance rénale chronique › Cystatin C as a predictor of mortality in...