Bail-out intracranial stenting with Solitaire AB device after unsuccessful thrombectomy in acute ischemic stroke of anterior circulation.


Journal

Journal of neuroradiology = Journal de neuroradiologie
ISSN: 0150-9861
Titre abrégé: J Neuroradiol
Pays: France
ID NLM: 7705086

Informations de publication

Date de publication:
Mar 2019
Historique:
received: 25 12 2017
revised: 26 04 2018
accepted: 25 05 2018
pubmed: 20 6 2018
medline: 30 7 2019
entrez: 20 6 2018
Statut: ppublish

Résumé

Recent trials established the efficacy of mechanical stent-retriever thrombectomy for treatment of stroke patients with large vessel occlusion (LVO) in the anterior circulation. However, stent-retriever thrombectomy may not accomplish successful recanalization in all patients. The aim of this study is to report the role of bail-out permanent stenting after failure of mechanical thrombectomy. Among 430 patients included in a prospectively maintained database, we analysed 325 cases of anterior circulation LVO. Mechanical thrombectomy (mTICI 2b-3) was effective in 213/325 (65%) and failed in 112/325 (35%). Bail-out intracranial stenting was performed in 17/325 (5.2%) patients. In all cases a fully retrievable detachable stent was used (Solitaire AB, Medtronic). No intraprocedural technical complications occurred. Successful reperfusion (mTICI 2b/3) was achieved in 12/17 patients (70.6%). Three (17.6%) patients died: one extensive infarction in the internal carotid artery territory, one large intracerebral haemorrhage, and one massive pulmonary embolism. Haemorrhagic conversion, both symptomatic and asymptomatic, occurred in 2/17 (11.7%). Good clinical outcome (mRS 0-2) at 3-months was achieved in 41.2% of patients. Bail-out intracranial stenting after unsuccessful thrombectomy is technically feasible and the associated haemorrhagic risk seems acceptable in selected patients. We suggest that bail-out intracranial stenting, is safe and effective in selected patients with LVO stroke who failed to respond to thrombectomy.

Sections du résumé

BACKGROUND BACKGROUND
Recent trials established the efficacy of mechanical stent-retriever thrombectomy for treatment of stroke patients with large vessel occlusion (LVO) in the anterior circulation. However, stent-retriever thrombectomy may not accomplish successful recanalization in all patients. The aim of this study is to report the role of bail-out permanent stenting after failure of mechanical thrombectomy.
METHODS METHODS
Among 430 patients included in a prospectively maintained database, we analysed 325 cases of anterior circulation LVO. Mechanical thrombectomy (mTICI 2b-3) was effective in 213/325 (65%) and failed in 112/325 (35%). Bail-out intracranial stenting was performed in 17/325 (5.2%) patients. In all cases a fully retrievable detachable stent was used (Solitaire AB, Medtronic).
RESULTS RESULTS
No intraprocedural technical complications occurred. Successful reperfusion (mTICI 2b/3) was achieved in 12/17 patients (70.6%). Three (17.6%) patients died: one extensive infarction in the internal carotid artery territory, one large intracerebral haemorrhage, and one massive pulmonary embolism. Haemorrhagic conversion, both symptomatic and asymptomatic, occurred in 2/17 (11.7%). Good clinical outcome (mRS 0-2) at 3-months was achieved in 41.2% of patients.
CONCLUSION CONCLUSIONS
Bail-out intracranial stenting after unsuccessful thrombectomy is technically feasible and the associated haemorrhagic risk seems acceptable in selected patients. We suggest that bail-out intracranial stenting, is safe and effective in selected patients with LVO stroke who failed to respond to thrombectomy.

Identifiants

pubmed: 29920349
pii: S0150-9861(17)30548-5
doi: 10.1016/j.neurad.2018.05.004
pii:
doi:

Types de publication

Journal Article

Langues

eng

Pagination

141-147

Informations de copyright

Copyright © 2018 Elsevier Masson SAS. All rights reserved.

Auteurs

Sergio Nappini (S)

Neurovascular Interventional Unit, Careggi University Hospital, Florence. Largo P. Palagi, 1-50134 Florence, Italy. Electronic address: nappini@gmail.com.

Nicola Limbucci (N)

Neurovascular Interventional Unit, Careggi University Hospital, Florence. Largo P. Palagi, 1-50134 Florence, Italy. Electronic address: nicolalimb@gmail.com.

Giuseppe Leone (G)

Department of Advanced Biomedical Sciences, Federico II University of Naples, Naples, Italy. Electronic address: g.leonemd@gmail.com.

Andrea Rosi (A)

Neurovascular Interventional Unit, Careggi University Hospital, Florence. Largo P. Palagi, 1-50134 Florence, Italy. Electronic address: andrea.rosi87@gmail.com.

Leonardo Renieri (L)

Neurovascular Interventional Unit, Careggi University Hospital, Florence. Largo P. Palagi, 1-50134 Florence, Italy. Electronic address: leonardo.renieri@hotmail.it.

Arturo Consoli (A)

Neurovascular Interventional Unit, Careggi University Hospital, Florence. Largo P. Palagi, 1-50134 Florence, Italy. Electronic address: onemed21@gmail.com.

Antonio Laiso (A)

Neurovascular Interventional Unit, Careggi University Hospital, Florence. Largo P. Palagi, 1-50134 Florence, Italy. Electronic address: antoniolaiso07@gmail.com.

Iacopo Valente (I)

Department of Bioimaging and Radiological Sciences, Institute of Radiology, "A. Gemelli" Hospital-Catholic University, Rome, Italy. Electronic address: iacopovalentemd@gmail.com.

Francesco Rosella (F)

Department of Bioimaging and Radiological Sciences, Institute of Radiology, "A. Gemelli" Hospital-Catholic University, Rome, Italy. Electronic address: francesco.rosella.md@gmail.com.

Riccardo Rosati (R)

Vascular and Interventional Radiology Unit, Department of Radiological, Oncological and Anatomo-pathological Sciences, Sapienza University of Rome, Rome, Italy. Electronic address: dopliker@yahoo.it.

Salvatore Mangiafico (S)

Neurovascular Interventional Unit, Careggi University Hospital, Florence. Largo P. Palagi, 1-50134 Florence, Italy. Electronic address: mangiax@libero.it.

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