Exhaled breath testing - A tool for the clinician and researcher.
Biomarkers
Exhaled biomarkers
Exhaled breath
Exhaled breath condensate
Volatile organic compounds [VOCs]
Journal
Paediatric respiratory reviews
ISSN: 1526-0550
Titre abrégé: Paediatr Respir Rev
Pays: England
ID NLM: 100898941
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
received:
09
05
2018
accepted:
09
05
2018
pubmed:
21
6
2018
medline:
16
8
2019
entrez:
21
6
2018
Statut:
ppublish
Résumé
Exhaled breath is a robust matrix of biomarkers divided between three fractions - gaseous breath, volatile breath, and breath condensate. Breath is collected non-invasively through bags (for gaseous breath), cold condensation chambers (breath condensate), and adsorbent traps (volatile breath). Due to the incredibly dilute nature of breath matrices, breath biomarker analysis requires precise analytical techniques, highly sensitive technology and often challenges the limit of detection of even the most advanced assays. Interest and advances in breath collection, analysis, and use have increased in recent years largely due to advances in analytical technology. Approved and validated breath tests are available as tools for researchers and clinicians. Novel development is ongoing. This article reviews the current applications for exhaled breath biomarkers.
Identifiants
pubmed: 29921519
pii: S1526-0542(18)30063-0
doi: 10.1016/j.prrv.2018.05.002
pii:
doi:
Substances chimiques
Biomarkers
0
Volatile Organic Compounds
0
Carbon Dioxide
142M471B3J
Nitric Oxide
31C4KY9ESH
Carbon Monoxide
7U1EE4V452
Hydrogen
7YNJ3PO35Z
Urea
8W8T17847W
Types de publication
Journal Article
Review
Langues
eng
Pagination
37-41Informations de copyright
Copyright © 2018 Elsevier Ltd. All rights reserved.