Research and Development of Proteins and Peptides with Therapeutic Potential from Yam Tubers.

Medicinal yam anti-cancer anti-microbial anti-oxidation immunomodulation menopause peptides proteins.

Journal

Current protein & peptide science
ISSN: 1875-5550
Titre abrégé: Curr Protein Pept Sci
Pays: United Arab Emirates
ID NLM: 100960529

Informations de publication

Date de publication:
2019
Historique:
received: 01 01 2018
revised: 10 04 2018
accepted: 24 05 2018
pubmed: 23 6 2018
medline: 3 8 2019
entrez: 23 6 2018
Statut: ppublish

Résumé

We discuss the diverse biological activities, therapeutic potential, and clinical applications of peptides and proteins isolated from various yams species including Dioscorea opposita Thunb (Chinese yam), D alata, D japonica (Japanese yam), D pseudojaponica, D batatas (Korea yam), and D cayenensis. Yam peptides and proteins have many pharmacological activities including immunomodulatory, antioxidant, estrogen-stimulating, osteogenic, angiotensin I-converting enzyme inhibiting, carbonic anhydrase and trypsin inhibiting, chitinase, anti-insect, anti-dust mite, lectin, and anti-proliferative activities. Yam peptides and proteins have therapeutic potential for treating cardiovascular diseases, inflammatory diseases, cancers, aging disorders, menopause, and osteoporosis.

Identifiants

pubmed: 29932033
pii: CPPS-EPUB-91207
doi: 10.2174/1389203719666180622094356
doi:

Substances chimiques

Peptides 0
Plant Proteins 0

Types de publication

Journal Article Review

Langues

eng

Pagination

277-284

Informations de copyright

Copyright© Bentham Science Publishers; For any queries, please email at epub@benthamscience.net.

Auteurs

Liang Zhang (L)

School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China.

Tzi Bun Ng (TB)

School of Biomedical Sciences, Faculty of Medicine, the Chinese University of Hong Kong, Hong Kong SAR, China.

Jenny Ka Wing Lam (JKW)

Department of Pharmacology and Pharmacy, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China.

Shi Wei Wang (SW)

School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China.

Lixing Lao (L)

School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China.

Kalin Yanbo Zhang (KY)

School of Chinese Medicine, Li Ka Shing Faculty of Medicine, the University of Hong Kong, Hong Kong SAR, China.

Stephen Cho Wing Sze (SCW)

Department of Biology, Faculty of Science, Hong Kong Baptisit University, Hong Kong SAR, China.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH