Relationship of para- and perirenal fat and epicardial fat with metabolic parameters in overweight and obese subjects.
Adolescent
Adult
Blood Glucose
Blood Pressure
Body Mass Index
Cross-Sectional Studies
Female
Humans
Insulin Resistance
/ physiology
Intra-Abdominal Fat
/ diagnostic imaging
Lipids
/ blood
Male
Middle Aged
Obesity
/ diagnostic imaging
Overweight
/ diagnostic imaging
Waist Circumference
/ physiology
Young Adult
Epicardial fat
Insulin resistance
Obesity
Para- and perirenal fat
Journal
Eating and weight disorders : EWD
ISSN: 1590-1262
Titre abrégé: Eat Weight Disord
Pays: Germany
ID NLM: 9707113
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
received:
27
02
2018
accepted:
18
06
2018
pubmed:
30
6
2018
medline:
22
5
2019
entrez:
30
6
2018
Statut:
ppublish
Résumé
The accumulation of visceral body fat, has been shown to be associated with higher risk of metabolic and cardiovascular disease. This study was addressed to examine whether para- and perirenal fat thickness and epicardial fat thickness were correlated with anthropometric- and cardiometabolic risk factors. A cohort of 102 uncomplicated overweight and obese patients was examined. BMI, waist circumference, blood pressure, fasting insulin, glucose, triglycerides, total cholesterol, HDL-cholesterol, LDL-cholesterol serum levels, and insulin resistance (assessed by HOMA PUFT was positively correlated with BMI (p < 0.001), waist circumference (p < 0.001), insulin (p < 0.001), HOMA This study shows that accumulation of central fat in apparently healthy overweight and obese subjects is associated to a simultaneous increase of pararenal, perirenal and epicardial fat. Moreover, it shows that only para- and perirenal fat is independently associated to insulin resistance and lower HDL-cholesterol, and only epicardial fat is independently associated to higher LDL cholesterol. Level of evidence Level V, cross-sectional descriptive study.
Sections du résumé
BACKGROUND
BACKGROUND
The accumulation of visceral body fat, has been shown to be associated with higher risk of metabolic and cardiovascular disease. This study was addressed to examine whether para- and perirenal fat thickness and epicardial fat thickness were correlated with anthropometric- and cardiometabolic risk factors.
METHODS
METHODS
A cohort of 102 uncomplicated overweight and obese patients was examined. BMI, waist circumference, blood pressure, fasting insulin, glucose, triglycerides, total cholesterol, HDL-cholesterol, LDL-cholesterol serum levels, and insulin resistance (assessed by HOMA
RESULTS
RESULTS
PUFT was positively correlated with BMI (p < 0.001), waist circumference (p < 0.001), insulin (p < 0.001), HOMA
CONCLUSIONS
CONCLUSIONS
This study shows that accumulation of central fat in apparently healthy overweight and obese subjects is associated to a simultaneous increase of pararenal, perirenal and epicardial fat. Moreover, it shows that only para- and perirenal fat is independently associated to insulin resistance and lower HDL-cholesterol, and only epicardial fat is independently associated to higher LDL cholesterol. Level of evidence Level V, cross-sectional descriptive study.
Identifiants
pubmed: 29956099
doi: 10.1007/s40519-018-0532-z
pii: 10.1007/s40519-018-0532-z
doi:
Substances chimiques
Blood Glucose
0
Lipids
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
67-72Commentaires et corrections
Type : CommentIn
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