Construction of Quaternary Stereocenters by Palladium-Catalyzed Carbopalladation-Initiated Cascade Reactions.

C−H functionalization asymmetric synthesis domino process homogeneous catalysis quaternary stereocenters

Journal

Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543

Informations de publication

Date de publication:
04 Feb 2019
Historique:
received: 27 05 2018
pubmed: 1 7 2018
medline: 1 7 2018
entrez: 1 7 2018
Statut: ppublish

Résumé

The enantioselective synthesis of molecules containing quaternary stereocenters is a field of intense research interest and development. Among the known organic transformations, carbopalladation-initiated domino transformations constitutes a general method for the construction of compounds containing cyclic or spiro quaternary stereocenters. In this Minireview, recent achievements in palladium-catalyzed domino Heck/C-H functionalizations and developments in enantioselective carbopalladation-initiated domino processes are summarized.

Identifiants

pubmed: 29959826
doi: 10.1002/anie.201806088
doi:

Types de publication

Journal Article Review

Langues

eng

Pagination

1562-1573

Subventions

Organisme : 1000-Youth Talents Plan
Organisme : National Natural Science Foundation of China
ID : 21702149
Organisme : Fundamental Research Funds for the Central Universities
ID : 2042018kf0012
Organisme : Swiss National Science Foundation (SNSF)

Informations de copyright

© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.

Auteurs

Yuanyuan Ping (Y)

The Institute for Advanced Studies, Wuhan University, Wuhan, 430072, P. R. China.

Yuxiu Li (Y)

The Institute for Advanced Studies, Wuhan University, Wuhan, 430072, P. R. China.

Jieping Zhu (J)

Laboratory of Synthesis and Natural Products, Institute of Chemical Sciences and Engineering, École Polytechnique Fédérale de Lausanne, EPFL-SB-ISIC-LSPN, BCH 5304, 1015, Lausanne, Switzerland.

Wangqing Kong (W)

The Institute for Advanced Studies, Wuhan University, Wuhan, 430072, P. R. China.

Classifications MeSH