Transient in-stent stenosis: a common finding after flow diverter implantation.


Journal

Journal of neurointerventional surgery
ISSN: 1759-8486
Titre abrégé: J Neurointerv Surg
Pays: England
ID NLM: 101517079

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 28 03 2018
revised: 21 05 2018
accepted: 29 05 2018
pubmed: 5 7 2018
medline: 14 3 2019
entrez: 5 7 2018
Statut: ppublish

Résumé

In recent years, implantation of flow diverters has emerged as an option for the endovascular treatment of intracranial aneurysms. One complication of treatment with flow diverters is the occurrence of in-stent stenosis, which has been reported to be partially reversible. The purpose of our study was to assess the incidence and dynamics of in-stent stenosis on angiographic short term and long term follow-up after treatment with flow diverters. A retrospective review of our prospectively maintained database identified all patients with intracranial internal carotid artery (ICA) aneurysms treated by flow diverters at our institution between 2014 and 2017. Clinical charts, procedural data, and angiographic results were reviewed. 18 patients were included. The mean short term follow-up was 92±19 days and mean long term follow-up was 449±120 days after treatment. No neurologic complications were observed. There was no procedure related mortality. Long term angiographic results showed complete occlusion in 83.3%, neck remnants in 11.1%, and incomplete occlusion in 5.5% of cases. In-stent stenosis was observed in all cases. Mean stenosis improved significantly from 30% on short term follow-up to 12% on long-term follow-up (P<0.0001). In-stent stenosis is a common finding on short term follow-up after the treatment with flow diverters but improves over time.

Sections du résumé

BACKGROUND AND PURPOSE OBJECTIVE
In recent years, implantation of flow diverters has emerged as an option for the endovascular treatment of intracranial aneurysms. One complication of treatment with flow diverters is the occurrence of in-stent stenosis, which has been reported to be partially reversible. The purpose of our study was to assess the incidence and dynamics of in-stent stenosis on angiographic short term and long term follow-up after treatment with flow diverters.
METHODS METHODS
A retrospective review of our prospectively maintained database identified all patients with intracranial internal carotid artery (ICA) aneurysms treated by flow diverters at our institution between 2014 and 2017. Clinical charts, procedural data, and angiographic results were reviewed.
RESULTS RESULTS
18 patients were included. The mean short term follow-up was 92±19 days and mean long term follow-up was 449±120 days after treatment. No neurologic complications were observed. There was no procedure related mortality. Long term angiographic results showed complete occlusion in 83.3%, neck remnants in 11.1%, and incomplete occlusion in 5.5% of cases. In-stent stenosis was observed in all cases. Mean stenosis improved significantly from 30% on short term follow-up to 12% on long-term follow-up (P<0.0001).
CONCLUSION CONCLUSIONS
In-stent stenosis is a common finding on short term follow-up after the treatment with flow diverters but improves over time.

Identifiants

pubmed: 29970620
pii: neurintsurg-2018-013975
doi: 10.1136/neurintsurg-2018-013975
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

196-199

Informations de copyright

© Article author(s) (or their employer(s) unless otherwise stated in the text of the article) 2019. All rights reserved. No commercial use is permitted unless otherwise expressly granted.

Déclaration de conflit d'intérêts

Competing interests: None declared.

Auteurs

Ruben Mühl-Benninghaus (R)

Department of Neuroradiology, Saarland University Hospital, Homburg/Saar, Germany.

Alena Haußmann (A)

Department of Neuroradiology, Saarland University Hospital, Homburg/Saar, Germany.

Andreas Simgen (A)

Department of Neuroradiology, Saarland University Hospital, Homburg/Saar, Germany.

Toshiki Tomori (T)

Department of Neuroradiology, Saarland University Hospital, Homburg/Saar, Germany.

Wolfgang Reith (W)

Department of Neuroradiology, Saarland University Hospital, Homburg/Saar, Germany.

Umut Yilmaz (U)

Department of Neuroradiology, Saarland University Hospital, Homburg/Saar, Germany.

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