An overview of Human Papillomavirus (HPV) as an etiological factor of the anal cancer.


Journal

Journal of infection and public health
ISSN: 1876-035X
Titre abrégé: J Infect Public Health
Pays: England
ID NLM: 101487384

Informations de publication

Date de publication:
Historique:
received: 08 10 2017
revised: 24 05 2018
accepted: 25 06 2018
pubmed: 8 7 2018
medline: 11 4 2019
entrez: 8 7 2018
Statut: ppublish

Résumé

Human papillomavirus (HPV) is a DNA tumour virus that is the primary cause of sexually transmitted infections (STIs). The direct connection between HPV and cervical cancer was discovered in 1980, however, many physicians and the general public are still oblivious to the association of HPV and anal cancer; most individuals find out about this relationship after a confirmed diagnosis, and therefore, it is important to raise awareness about HPV as an etiological agent in anal cancer. There is a quadrivalent vaccine available, which prevents an individual from being infected with HPV, thus anal cancer is mainly a preventable cancer when caused by HPV, and ultimately, preventing cancer is better than curing cancer, especially when there is no definite cure.This article aims to review the microbiology, pathophysiology, epidemiology, clinical presentation, diagnostic evaluation, prophylaxis and treatment options for HPV as an etiology agent in anal cancers in light of recent literature.

Identifiants

pubmed: 29980478
pii: S1876-0341(18)30101-1
doi: 10.1016/j.jiph.2018.06.005
pii:
doi:

Substances chimiques

Papillomavirus Vaccines 0

Types de publication

Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

1-6

Informations de copyright

Copyright © 2018 The Authors. Published by Elsevier Ltd.. All rights reserved.

Auteurs

Joanna Krzowska-Firych (J)

Department of Infectious Diseases, Medical University of Lublin, Poland; Clinical Research Association for Infectious Disease at the Department of Infectious Diseases, Medical University of Lublin, Poland.

Georgia Lucas (G)

Clinical Research Association for Infectious Disease at the Department of Infectious Diseases, Medical University of Lublin, Poland.

Christiana Lucas (C)

Clinical Research Association for Infectious Disease at the Department of Infectious Diseases, Medical University of Lublin, Poland.

Nicholas Lucas (N)

Clinical Research Association for Infectious Disease at the Department of Infectious Diseases, Medical University of Lublin, Poland.

Łukasz Pietrzyk (Ł)

Department of General, Oncological and Minimally Invasive Surgery, 1st Military Clinical Hospital with the Outpatient Clinic in Lublin, Poland; Department of Didactics and Medical Simulation, Chair of Anatomy, Medical University of Lublin, Poland. Electronic address: lukasz.pietrzyk@wp.pl.

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Classifications MeSH