IMproved MAnagement (IM-MA study) in cancer-related pain: the value of a joint approach by an integrated team of radiotherapist and anesthetist.


Journal

Supportive care in cancer : official journal of the Multinational Association of Supportive Care in Cancer
ISSN: 1433-7339
Titre abrégé: Support Care Cancer
Pays: Germany
ID NLM: 9302957

Informations de publication

Date de publication:
Feb 2019
Historique:
received: 18 11 2017
accepted: 26 06 2018
pubmed: 8 7 2018
medline: 23 2 2019
entrez: 8 7 2018
Statut: ppublish

Résumé

Purpose of this study was to retrospectively review our experience of multidisciplinary clinic providing a joint approach by radiation oncologist and anesthetist for patients with cancer pain to evaluate the adequacy and the IMprovement in MAnagement (IM-MA study) of this symptom. A Team for Pain Management (TPM) represented by radiation oncologist and anesthetist weekly provided consultations to patient presenting cancer pain. TPM prospectively reported epidemiologic, symptomatic, and pharmacological data. TPM modified pain therapy and indicated antalgic radiotherapy. Patients were evaluated at baseline and after 4 weeks after intervention. From November 2015 to April 2016, 65 patients were evaluated by TPM. At the baseline, 18 patients (27.7%) were undertreated (i.e., receiving inadequate pain management); furthermore, 27 patients (41.5%) despite receiving strong opioids had uncontrolled pain. After 4 weeks from intervention, undertreated patients were reduced to 1.53%. For those patients undergone to radiotherapy, response at 34 weeks was scored as follows: complete response 28.8%, partial response 46.7%, pain progression 0.95%, indeterminate response 23.8%. A multidisciplinary Team for Pain Management improved the clinical management, optimizing pain control and increasing adequacy of pharmacological management. The TPM intervention seems particularly worth for patients presenting specific features including BTcP, neuropathic pain, severe pain due to bone metastases, and any potential candidate to radiotherapy. Larger series and QoL questionnaires are required to confirm these results.

Identifiants

pubmed: 29980908
doi: 10.1007/s00520-018-4335-6
pii: 10.1007/s00520-018-4335-6
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

505-512

Références

Radiother Oncol. 2002 Sep;64(3):275-80
pubmed: 12242115
J Pain Symptom Manage. 2004 Jan;27(1):1-3
pubmed: 14711462
Ann Oncol. 2007 Sep;18(9):1437-49
pubmed: 17355955
Ann Oncol. 2008 Jan;19(1):5-7
pubmed: 18073220
J Palliat Med. 2007 Dec;10(6):1338-46
pubmed: 18095813
Support Care Cancer. 2008 Nov;16(11):1203-11
pubmed: 18478276
J Pain Symptom Manage. 2009 Jan;37(1):77-84
pubmed: 18504094
Ann Oncol. 2008 Dec;19(12):1985-91
pubmed: 18632721
Br J Cancer. 2009 May 19;100(10):1566-74
pubmed: 19401688
Int J Radiat Oncol Biol Phys. 2010 Oct 1;78(2):527-32
pubmed: 20100640
J Palliat Med. 2010 May;13(5):589-93
pubmed: 20408764
Int J Radiat Oncol Biol Phys. 2012 Apr 1;82(5):1730-7
pubmed: 21489705
J Oncol Pharm Pract. 2012 Mar;18(1):76-83
pubmed: 21490115
Palliat Med. 2011 Jul;25(5):398-401
pubmed: 21708847
Lancet Oncol. 2012 Feb;13(2):e58-68
pubmed: 22300860
Ann Oncol. 2012 Aug;23(8):2016-20
pubmed: 22565123
Arthritis Care Res (Hoboken). 2011 Nov;63 Suppl 11:S240-52
pubmed: 22588748
Ann Oncol. 2012 Sep;23 Suppl 10:x294-301
pubmed: 22987980
Ann Oncol. 2012 Oct;23 Suppl 7:vii139-54
pubmed: 22997447
Clin J Pain. 2013 Nov;29(11):944-7
pubmed: 23370088
J Clin Oncol. 2014 Dec 20;32(36):4149-54
pubmed: 25403222
Radiat Oncol. 2015 Mar 07;10:61
pubmed: 25889414
Support Care Cancer. 2016 Feb;24(2):887-892
pubmed: 26209950
J Bone Oncol. 2015 Jan 23;4(1):13-7
pubmed: 26579484
N Engl J Med. 1994 Mar 3;330(9):592-6
pubmed: 7508092
Pain. 1995 May;61(2):277-84
pubmed: 7659438
J Pain Symptom Manage. 1998 Sep;16(3):171-8
pubmed: 9769619

Auteurs

S Manfrida (S)

Department of Radiation Oncology, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

V Masiello (V)

Department of Radiation Oncology, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy. valeria.masiello@guest.policlinicogemelli.it.

F Cellini (F)

Department of Radiation Oncology, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

E Adducci (E)

Department of Anesthesiology, Intensive Care and Pain Therapy, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

L Polidori (L)

Department of Anesthesiology, Intensive Care and Pain Therapy, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

S Longo (S)

Department of Radiation Oncology, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

G Cannelli (G)

Department of Anesthesiology, Intensive Care and Pain Therapy, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

M Balducci (M)

Department of Radiation Oncology, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

M Rossi (M)

Department of Anesthesiology, Intensive Care and Pain Therapy, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

V Valentini (V)

Department of Radiation Oncology, Fondazione Policlinico A. Gemelli IRCCS, Catholic University of the Sacred Heart, Rome, Italy.

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Classifications MeSH