Limbic encephalitis as a relapse of Whipple's disease with digestive involvement and spondylodiscitis.
Emerging infectious disease
Limbic encephalitis
Tropheryma whipplei
Whipple’s disease
Journal
Infection
ISSN: 1439-0973
Titre abrégé: Infection
Pays: Germany
ID NLM: 0365307
Informations de publication
Date de publication:
Aug 2019
Aug 2019
Historique:
received:
28
12
2017
accepted:
04
07
2018
pubmed:
11
7
2018
medline:
13
11
2019
entrez:
11
7
2018
Statut:
ppublish
Résumé
Many clinical manifestations can be related to Tropheryma whipplei infection. We report a Tropheryma whipplei limbic encephalitis developed as a relapse of classical Whipple's disease. This case is to the best of our knowledge the first proof of the effective brain-blood barrier crossing of both doxycycline and hydroxychloroquine as demonstrated by direct concentration monitoring on brain biopsy.
Identifiants
pubmed: 29987509
doi: 10.1007/s15010-018-1173-x
pii: 10.1007/s15010-018-1173-x
doi:
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
637-641Références
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