Exploring the relationship between fairness and 'brain types' in children with high-functioning autism spectrum disorder.


Journal

Progress in neuro-psychopharmacology & biological psychiatry
ISSN: 1878-4216
Titre abrégé: Prog Neuropsychopharmacol Biol Psychiatry
Pays: England
ID NLM: 8211617

Informations de publication

Date de publication:
10 01 2019
Historique:
received: 02 04 2018
revised: 02 07 2018
accepted: 09 07 2018
pubmed: 17 7 2018
medline: 19 3 2019
entrez: 17 7 2018
Statut: ppublish

Résumé

Existing research typically focuses on only one domain of cognition with regard to fairness-theory of mind or executive function. However, children with High-functioning autism spectrum disorder (HF-ASD) are cognitively impaired in both domains. Moreover, little is known about fairness characteristics in children with HF-ASD in relation to both domains of cognition. Thirty children with HF-ASD as well as 39 children with typical development (TD) were evaluated in this study. We investigated the development of children's fairness characteristics as a responder in a mini ultimatum game (UG). The different 'brain types,' i.e., with or without HF-ASD, were evaluated using the Empathy Questionnaire-Systemizing Questionnaire (E/SC-Q). Furthermore, we explored the relationship between fairness and brain types using Pearson correlation analyses. Children in the HF-ASD group were more likely to accept unfair offers than were children in the TD group (χ Our findings show that children with HF-ASD were more likely to accept an unfair offer; in particular, the more unbalanced the development of empathy and systemizing was, the more significant the unfairness preference observed. Extreme Type S positively predicted the acceptance of unfair offers by children with HF-ASD. World Health Organization class I registered international clinical trial platform, ChiCTR-ROC-17012877.

Sections du résumé

BACKGROUND
Existing research typically focuses on only one domain of cognition with regard to fairness-theory of mind or executive function. However, children with High-functioning autism spectrum disorder (HF-ASD) are cognitively impaired in both domains. Moreover, little is known about fairness characteristics in children with HF-ASD in relation to both domains of cognition.
METHODS
Thirty children with HF-ASD as well as 39 children with typical development (TD) were evaluated in this study. We investigated the development of children's fairness characteristics as a responder in a mini ultimatum game (UG). The different 'brain types,' i.e., with or without HF-ASD, were evaluated using the Empathy Questionnaire-Systemizing Questionnaire (E/SC-Q). Furthermore, we explored the relationship between fairness and brain types using Pearson correlation analyses.
RESULTS
Children in the HF-ASD group were more likely to accept unfair offers than were children in the TD group (χ
DISCUSSION
Our findings show that children with HF-ASD were more likely to accept an unfair offer; in particular, the more unbalanced the development of empathy and systemizing was, the more significant the unfairness preference observed. Extreme Type S positively predicted the acceptance of unfair offers by children with HF-ASD.
REGISTRATION OF CLINICAL TRIALS
World Health Organization class I registered international clinical trial platform, ChiCTR-ROC-17012877.

Identifiants

pubmed: 30009870
pii: S0278-5846(18)30242-2
doi: 10.1016/j.pnpbp.2018.07.008
pii:
doi:

Banques de données

ChiCTR
['ChiCTR-ROC-17012877']

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

151-158

Informations de copyright

Copyright © 2018 The Authors. Published by Elsevier Inc. All rights reserved.

Auteurs

Yao Wang (Y)

The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210009, China; The Fourth People's Hospital of Taizhou, Taizhou, Jiangsu Province 225300, China.

Yunhua Xiao (Y)

The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210009, China.

Yun Li (Y)

The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210009, China.

Kangkang Chu (K)

The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210009, China.

Min Feng (M)

The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210009, China.

Chunyan Li (C)

The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210009, China.

Nana Qiu (N)

The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210009, China.

Jiao Weng (J)

The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210009, China.

Xiaoyan Ke (X)

The Affiliated Brain Hospital of Nanjing Medical University, Nanjing, Jiangsu Province 210009, China. Electronic address: kexiaoyan@njmu.edu.cn.

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