Estrogen receptors and sex hormone binding globulin in neuronal cells and tissue.


Journal

Steroids
ISSN: 1878-5867
Titre abrégé: Steroids
Pays: United States
ID NLM: 0404536

Informations de publication

Date de publication:
02 2019
Historique:
received: 16 06 2017
revised: 15 03 2018
accepted: 27 06 2018
pubmed: 22 7 2018
medline: 7 6 2019
entrez: 22 7 2018
Statut: ppublish

Résumé

Estrogens exert a critical influence on neuronal tissues and cells. As demonstrated in many clinical studies, estrogens are neuroprotective to the extent that they improve prognosis for women with neurodegenerative diseases. Unfortunately, we still do not know exactly how these effects are mediated. Fifty years ago the first estrogen receptor was found, but since then many other new pathways of estrogen action have been identified. This review describes several of these pathways of estrogen effects and provides some conclusions and correlations about these as determined by recent studies with nerve growth factor differentiated rat pheochromocytoma cell line.

Identifiants

pubmed: 30030052
pii: S0039-128X(18)30125-9
doi: 10.1016/j.steroids.2018.06.015
pii:
doi:

Substances chimiques

Receptors, Estrogen 0
Sex Hormone-Binding Globulin 0

Types de publication

Journal Article Research Support, Non-U.S. Gov't Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

94-99

Informations de copyright

Copyright © 2018. Published by Elsevier Inc.

Auteurs

Veronika M Gebhart (VM)

Institute of Anatomy II, University Hospital Jena, Germany. Electronic address: veronika.gebhart@med.uni-jena.de.

Jack D Caldwell (JD)

Department of Pharmacology, Edward Via College of Osteopathic Medicine, Spartanburg, SC, United States.

Andrea Rodewald (A)

Institute of Anatomy II, University Hospital Jena, Germany.

Konstantina Kalyvianaki (K)

Laboratory of Experimental Endocrinology, University of Crete, School of Medicine, Heraklion, Greece.

Marilena Kampa (M)

Laboratory of Experimental Endocrinology, University of Crete, School of Medicine, Heraklion, Greece.

Gustav F Jirikowski (GF)

Institute of Anatomy II, University Hospital Jena, Germany.

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Classifications MeSH