Cryptotanshinone from Salvia miltiorrhiza Roots Reduces Cytokeratin CK1/10 Expression in Keratinocytes by Activation of Peptidyl-prolyl-cis-trans-isomerase FKBP1A.

Cell Differentiation / drug effects Cell Line Enzyme Activation / drug effects Filaggrin Proteins Humans Keratinocytes / drug effects Phenanthrenes / pharmacology Plant Extracts / pharmacology Salvia miltiorrhiza / chemistry Tacrolimus Binding Proteins / metabolism

Journal

Planta medica
ISSN: 1439-0221
Titre abrégé: Planta Med
Pays: Germany
ID NLM: 0066751

Informations de publication

Date de publication:
May 2019
Historique:
pubmed: 24 7 2018
medline: 14 6 2019
entrez: 24 7 2018
Statut: ppublish

Résumé

Cryptotanshinone (CTS) (1 µM) from the roots of

Identifiants

DOI: 10.1055/a-0660-0441 PMID: 30036889
pubmed: 30036889
doi: 10.1055/a-0660-0441
doi:

Substances chimiques

FKBP1A protein, human 0
FLG protein, human 0
Filaggrin Proteins 0
Phenanthrenes 0
Plant Extracts 0
cryptotanshinone 5E9SXT166N
Tacrolimus Binding Proteins EC 5.2.1.-

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

552-562

Informations de copyright

Georg Thieme Verlag KG Stuttgart · New York.

Déclaration de conflit d'intérêts

The authors declare no conflict of interest.

Auteurs

Stefan Esch (S)

University of Münster, Institute of Pharmaceutical Biology and Phytochemistry, Münster, Germany.

Simone König (S)

University of Münster, Interdisciplinary Centre for Clinical Research, Core Unit Proteomics, Münster, Germany.

Bertan Bopp (B)

University of Münster, Institute of Pharmaceutical and Medicinal Chemistry, Münster, Germany.

Joachim Jose (J)

University of Münster, Institute of Pharmaceutical and Medicinal Chemistry, Münster, Germany.

Simone Brandt (S)

University of Münster, Institute of Pharmaceutical Biology and Phytochemistry, Münster, Germany.

Andreas Hensel (A)

University of Münster, Institute of Pharmaceutical Biology and Phytochemistry, Münster, Germany.

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Classifications MeSH

questionsmedicales.fr › Phénomènes physiologiques cellulaires › Différenciation cellulaire › Cryptotanshinone from Salvia miltiorrhiza...
questionsmedicales.fr › Cellules › Cellules cultivées › Lignée cellulaire › Cryptotanshinone from Salvia miltiorrhiza...
questionsmedicales.fr › Métabolisme › Activation enzymatique › Cryptotanshinone from Salvia miltiorrhiza...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Protéines de tissu nerveux › Protéines S100 › Protéines filaggrine › Cryptotanshinone from Salvia miltiorrhiza...
questionsmedicales.fr › Eucaryotes › Animaux › Chordés › Vertébrés › Mammifères › Eutheria › Primates › Haplorhini › Catarrhini › Hominidae › Humains › Cryptotanshinone from Salvia miltiorrhiza...
questionsmedicales.fr › Cellules › Cellules épithéliales › Kératinocytes › Cryptotanshinone from Salvia miltiorrhiza...
questionsmedicales.fr › Composés polycycliques › Hydrocarbures aromatiques polycycliques › Phénanthrènes › Cryptotanshinone from Salvia miltiorrhiza...
questionsmedicales.fr › Préparations pharmaceutiques › Extraits de plantes › Cryptotanshinone from Salvia miltiorrhiza...
questionsmedicales.fr › Eucaryotes › Viridiplantae › Streptophyta › Embryophyta › Tracheobionta › Magnoliopsida › Lamiales › Lamiaceae › Salvia › Salvia miltiorrhiza › Cryptotanshinone from Salvia miltiorrhiza...
questionsmedicales.fr › Acides aminés, peptides et protéines › Protéines › Récepteurs des médicaments › Immunophilines › Protéines de liaison au tacrolimus › Cryptotanshinone from Salvia miltiorrhiza...