Menstruation-related disseminated intravascular coagulation in an adenomyosis patient: case report and review of the literature.


Journal

Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
ISSN: 1473-0766
Titre abrégé: Gynecol Endocrinol
Pays: England
ID NLM: 8807913

Informations de publication

Date de publication:
Jan 2019
Historique:
pubmed: 26 7 2018
medline: 14 6 2019
entrez: 26 7 2018
Statut: ppublish

Résumé

Disseminated intravascular coagulation (DIC) is a high mortality coagulopathy that leads to simultaneous thrombotic and bleeding problems. It occurs as a complication in different disease as malignancies, obstetrical catastrophes, bacterial sepsis and traumas. We report on an extremely rare case of acute DIC in a patient with misdiagnosed adenomyosis and massive methrorragia which led to acute kidney failure. The patient was successfully treated with hysterectomy and blood product transfusions; however, a slight reduction of renal function persisted. We were able to confirm the cause-consequence link between adenomyosis and consumptive DIC since we saw the thrombi in the adenomyotic uterus from early hysterectomy specimen. Moreover, this is the first case, for the best of our knowledge, in which systemic consequences persist in an adenomyosis patient who developed a DIC. Early diagnose and treatment of acute DIC is essential for patient's survival and to prevent severe complications: adenomyosis should be kept in mind as a possible cause of DIC when a patient shows up with massive bleeding.

Identifiants

pubmed: 30044152
doi: 10.1080/09513590.2018.1488956
doi:

Types de publication

Case Reports Journal Article Review

Langues

eng

Sous-ensembles de citation

IM

Pagination

32-35

Auteurs

Alice Cernogoraz (A)

a Department of Medical Science , Università di Trieste , Trieste , Italy.
b Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" , Trieste , Italy.

Luigi Schiraldi (L)

a Department of Medical Science , Università di Trieste , Trieste , Italy.

Deborah Bonazza (D)

c Clinical Unit of Pathological Anatomy and Histology, Department of Medical Science , University of Trieste , Trieste , Italy.

Giuseppe Ricci (G)

a Department of Medical Science , Università di Trieste , Trieste , Italy.
b Institute for Maternal and Child Health-IRCCS "Burlo Garofolo" , Trieste , Italy.

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Classifications MeSH