Lemierre Syndrome: Clinical Update and Protocol for a Systematic Review and Individual Patient Data Meta-analysis.


Journal

Hamostaseologie
ISSN: 2567-5761
Titre abrégé: Hamostaseologie
Pays: Germany
ID NLM: 8204531

Informations de publication

Date de publication:
Feb 2019
Historique:
pubmed: 3 8 2018
medline: 20 8 2019
entrez: 3 8 2018
Statut: ppublish

Résumé

Lemierre syndrome usually affects otherwise healthy adolescents or young adults and occurs at an overall rate of 1 to 10 cases per million person-years with an estimated fatality rate of 4 to 9%. Diagnostic criteria remain debated and include acute neck/head bacterial infection (often tonsillitis caused by anaerobes at high potential for sepsis and vascular invasion, notably Das Lemierre-Syndrom betrifft normalerweise gesunde Jugendliche oder junge Erwachsene und tritt mit einer Gesamttodesrate von 1 bis 10 Fällen pro Million Personenjahre mit einer geschätzten Sterblichkeitsrate von 4 bis 9% auf. Diagnostische Kriterien bleiben umstritten und umfassen akute Kopf-Hals-Bakterieninfektionen (häufig Tonsillitis durch Anaerobier mit hohem Sepsis-und Gefäßinvasionspotenzial, insbesondere

Autres résumés

Type: Publisher (ger)
Das Lemierre-Syndrom betrifft normalerweise gesunde Jugendliche oder junge Erwachsene und tritt mit einer Gesamttodesrate von 1 bis 10 Fällen pro Million Personenjahre mit einer geschätzten Sterblichkeitsrate von 4 bis 9% auf. Diagnostische Kriterien bleiben umstritten und umfassen akute Kopf-Hals-Bakterieninfektionen (häufig Tonsillitis durch Anaerobier mit hohem Sepsis-und Gefäßinvasionspotenzial, insbesondere

Identifiants

pubmed: 30071559
doi: 10.1055/s-0038-1654720
doi:

Substances chimiques

Anti-Bacterial Agents 0
Anticoagulants 0

Types de publication

Case Reports Journal Article Meta-Analysis Systematic Review

Langues

eng

Pagination

76-86

Informations de copyright

Georg Thieme Verlag KG Stuttgart · New York.

Déclaration de conflit d'intérêts

Marcello Di Nisio reports personal fees from Daiichi and Bayer HealthCare. Stavros Konstantinides has received consultancy, advisory board and lecture fees from Bayer HealthCare, Boehringer Ingelheim, Merck Sharp & Dohme, Daiichi-Sankyo, Pfizer–Bristol-Myers Squibb and BTG Biocompatibles Group UK; and institutional grants from Boehringer Ingelheim, Bayer HealthCare, Daiichi-Sankyo, Merck Sharp & Dohme-Pfizer and Actelion. All the other authors do not report any potential conflict of interest for the present publication.The work of Stavros Konstantinides and Stefano Barco is supported by the German Federal Ministry of Education and Research (BMBF 01EO1003 and 01EO1503).

Auteurs

Clara Sacco (C)

Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.

Federica Zane (F)

Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.

Serena Granziera (S)

Department of Medicine (DIMED), Geriatric Clinic, University of Padua, Padua, Italy.
Department of Physical and Rehabilitation Medicine, "Villa Salus" Hospital, Mestre, Italy.

Karin Holm (K)

Division of Infection Medicine, Department of Clinical Sciences, Lund University, Lund, Sweden.

Dina Creemers-Schild (D)

Department of Internal Medicine, Langeland Hospital, Zoetermeer, The Netherlands.

Michel-André Hotz (MA)

Department of ENT, Head and Neck Surgery, Inselspital (University Hospital of Bern), University of Bern, Bern, Switzerland.

Elena Turpini (E)

Department of Radiology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.

Adele Valentini (A)

Department of Radiology, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.

Christian Righini (C)

Department of Otolaryngology-Head and Neck Surgery, Grenoble University Hospital, Grenoble, France.

Petros D Karkos (PD)

Department of Otolaryngology-Head and Neck Surgery, AHEPA Hospital, Aristotle University of Thessaloniki, Thessaloniki, Greece.

Peter Verhamme (P)

Department of Vascular Medicine and Haemostasis, University Hospitals Leuven, Leuven, Belgium.

Marcello Di Nisio (M)

Department of Medicine and Ageing Sciences, University G. D'Annunzio of Chieti-Pescara, Chieti, Italy.

Stavros Konstantinides (S)

Center for Thrombosis and Haemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.
Department of Cardiology, Democritus University of Thrace, Alexandroupolis, Greece.

Alessandro Pecci (A)

Department of Internal Medicine, IRCCS Policlinico San Matteo Foundation, University of Pavia, Pavia, Italy.

Stefano Barco (S)

Center for Thrombosis and Haemostasis, University Medical Center of the Johannes Gutenberg University, Mainz, Germany.

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Classifications MeSH