On the Use of Infrared Thermography for Monitoring a Vial Freeze-Drying Process.
IR camera
freeze-drying
monitoring
process analytical technology
sensor
temperature
Journal
Journal of pharmaceutical sciences
ISSN: 1520-6017
Titre abrégé: J Pharm Sci
Pays: United States
ID NLM: 2985195R
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
26
06
2018
revised:
23
07
2018
accepted:
26
07
2018
pubmed:
6
8
2018
medline:
18
2
2020
entrez:
6
8
2018
Statut:
ppublish
Résumé
Monitoring a vial freeze-drying process without interfering with product dynamics is a challenging issue. This article presents a novel device constituted by an infrared camera designed to be placed inside the drying chamber, able to monitor the temperature of the vials, very close to that of the product inside. By this way it is possible to estimate the ending point of the primary drying, the heat transfer coefficient to the product (K
Identifiants
pubmed: 30077699
pii: S0022-3549(18)30482-9
doi: 10.1016/j.xphs.2018.07.025
pii:
doi:
Substances chimiques
Sucrose
57-50-1
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
391-398Informations de copyright
Copyright © 2019 American Pharmacists Association®. Published by Elsevier Inc. All rights reserved.