Tunable Orthogonal Reversible Covalent (TORC) Bonds: Dynamic Chemical Control over Molecular Assembly.
dynamic covalent chemistry
dynamic materials
molecular assembly
molecular recognition
orthogonality
Journal
Angewandte Chemie (International ed. in English)
ISSN: 1521-3773
Titre abrégé: Angew Chem Int Ed Engl
Pays: Germany
ID NLM: 0370543
Informations de publication
Date de publication:
02 01 2019
02 01 2019
Historique:
received:
21
07
2018
pubmed:
12
8
2018
medline:
1
8
2020
entrez:
12
8
2018
Statut:
ppublish
Résumé
Dynamic assembly of macromolecules in biological systems is one of the fundamental processes that facilitates life. Although such assembly most commonly uses noncovalent interactions, a set of dynamic reactions involving reversible covalent bonding is actively being exploited for the design of functional materials, bottom-up assembly, and molecular machines. This Minireview highlights recent implementations and advancements in the area of tunable orthogonal reversible covalent (TORC) bonds for these purposes, and provides an outlook for their expansion, including the development of synthetically encoded polynucleotide mimics.
Identifiants
pubmed: 30098086
doi: 10.1002/anie.201808371
doi:
Substances chimiques
Macromolecular Substances
0
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Research Support, U.S. Gov't, Non-P.H.S.
Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
74-85Subventions
Organisme : Division of Materials Research
ID : DMR-1720595
Pays : International
Organisme : Defense Advanced Research Projects Agency
ID : N66001-14-2-4051
Pays : International
Organisme : Welch Foundation
ID : F-0046
Pays : International
Organisme : NIH HHS
ID : 1R01EB022025-01A1
Pays : United States
Informations de copyright
© 2019 Wiley-VCH Verlag GmbH & Co. KGaA, Weinheim.