Does Abdominal Obesity Accelerate Muscle Strength Decline in Older Adults? Evidence From the English Longitudinal Study of Ageing.
Aged
Aging
/ physiology
Body Mass Index
Disability Evaluation
England
/ epidemiology
Female
Health Status
Humans
Life Style
Longitudinal Studies
Male
Mental Health
Middle Aged
Muscle Strength
Muscle Strength Dynamometer
Obesity, Abdominal
/ diagnosis
Risk Assessment
/ methods
Sex Factors
Socioeconomic Factors
Waist Circumference
Grip strength
Longitudinal
Trajectories
Waist circumference
Journal
The journals of gerontology. Series A, Biological sciences and medical sciences
ISSN: 1758-535X
Titre abrégé: J Gerontol A Biol Sci Med Sci
Pays: United States
ID NLM: 9502837
Informations de publication
Date de publication:
18 06 2019
18 06 2019
Historique:
received:
15
03
2018
pubmed:
15
8
2018
medline:
23
4
2020
entrez:
15
8
2018
Statut:
ppublish
Résumé
Cross-sectional evidence has shown an association between abdominal obesity and lower muscle strength in older adults. However, no longitudinal findings have confirmed this association. In addition, the impact of abdominal fat on the reduction in muscle strength is not yet fully understood. We investigated the longitudinal associations between abdominal obesity and handgrip strength in 5,181 older adults from the English Longitudinal Study of Ageing over 8 years of follow-up. Muscular strength was measured using a manual dynamometer. Abdominal obesity was defined as a waist circumference >102 cm for men and >88 cm for women. Generalized linear mixed models were adjusted by measures of socioeconomic status, health conditions, lifestyle, cognition, depressive symptoms, biomarkers, and disability. At baseline, the mean age of participants was 65.8 years and their mean waist circumference and body mass index (BMI) were 95 cm and 27.7 kg/m2, respectively. Fully adjusted models showed that abdominal obese men and women had stronger muscle strength at baseline. The decline over time in muscle strength was accelerated in abdominal obese men (-0.12 kg/year, 95% confidence interval: -0.24 to -0.01) compared with nonabdominal obese. This association was not found in women. Comparative analyses showed that overweight men according to their BMI were not at greater risk of muscle strength decline. However, these men were at risk based on their waist circumference. Abdominal obesity is associated with accelerated muscle strength decline in men.
Sections du résumé
BACKGROUND
Cross-sectional evidence has shown an association between abdominal obesity and lower muscle strength in older adults. However, no longitudinal findings have confirmed this association. In addition, the impact of abdominal fat on the reduction in muscle strength is not yet fully understood.
METHODS
We investigated the longitudinal associations between abdominal obesity and handgrip strength in 5,181 older adults from the English Longitudinal Study of Ageing over 8 years of follow-up. Muscular strength was measured using a manual dynamometer. Abdominal obesity was defined as a waist circumference >102 cm for men and >88 cm for women. Generalized linear mixed models were adjusted by measures of socioeconomic status, health conditions, lifestyle, cognition, depressive symptoms, biomarkers, and disability.
RESULTS
At baseline, the mean age of participants was 65.8 years and their mean waist circumference and body mass index (BMI) were 95 cm and 27.7 kg/m2, respectively. Fully adjusted models showed that abdominal obese men and women had stronger muscle strength at baseline. The decline over time in muscle strength was accelerated in abdominal obese men (-0.12 kg/year, 95% confidence interval: -0.24 to -0.01) compared with nonabdominal obese. This association was not found in women. Comparative analyses showed that overweight men according to their BMI were not at greater risk of muscle strength decline. However, these men were at risk based on their waist circumference.
CONCLUSIONS
Abdominal obesity is associated with accelerated muscle strength decline in men.
Identifiants
pubmed: 30107482
pii: 5068954
doi: 10.1093/gerona/gly178
pmc: PMC6580692
doi:
Types de publication
Journal Article
Research Support, N.I.H., Extramural
Research Support, Non-U.S. Gov't
Langues
eng
Sous-ensembles de citation
IM
Pagination
1105-1111Subventions
Organisme : NIA NIH HHS
ID : R01 AG017644
Pays : United States
Informations de copyright
© The Author(s) 2018. Published by Oxford University Press on behalf of The Gerontological Society of America.
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