Computed tomography pulmonary angiography
Angiography
/ adverse effects
Female
Fetus
Humans
Lung
/ diagnostic imaging
Pregnancy
Pregnancy Complications, Cardiovascular
/ diagnostic imaging
Prenatal Exposure Delayed Effects
Pulmonary Embolism
/ diagnostic imaging
Radiation Exposure
/ adverse effects
Tomography, X-Ray Computed
/ adverse effects
Journal
Haematologica
ISSN: 1592-8721
Titre abrégé: Haematologica
Pays: Italy
ID NLM: 0417435
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
received:
23
04
2017
accepted:
14
08
2018
pubmed:
18
8
2018
medline:
30
4
2020
entrez:
18
8
2018
Statut:
ppublish
Résumé
Differences between computed tomography pulmonary angiography and ventilation-perfusion lung scanning in pregnant patients with suspected acute pulmonary embolism are not well-known, leading to ongoing debate on which test to choose. We searched in PubMed, EMBASE, Web of Science and the Cochrane Library databases and identified all relevant articles and abstracts published up to October 1, 2017. We assessed diagnostic efficiency, frequency of non-diagnostic results and maternal and fetal exposure to radiation exposure. We included 13 studies for the diagnostic efficiency analysis, 30 for the analysis of non-diagnostic results and 22 for the radiation exposure analysis. The pooled rate of false negative test results was 0% for both imaging strategies with overlapping confidence intervals. The pooled rates of non-diagnostic results with computed tomography pulmonary angiography and ventilation-perfusion lung scans were 12% (95% confidence interval: 8-17) and 14% (95% confidence interval: 10-18), respectively. Reported maternal and fetal radiation exposure doses were well below the safety threshold, but could not be compared between the two diagnostic methods given the lack of high quality data. Both imaging tests seem equally safe to rule out pulmonary embolism in pregnancy. We found no significant differences in efficiency and radiation exposures between computed tomography pulmonary angiography and ventilation-perfusion lung scanning although direct comparisons were not possible.
Identifiants
pubmed: 30115658
pii: haematol.2018.196121
doi: 10.3324/haematol.2018.196121
pmc: PMC6312023
doi:
Types de publication
Journal Article
Meta-Analysis
Systematic Review
Langues
eng
Sous-ensembles de citation
IM
Pagination
176-188Commentaires et corrections
Type : CommentIn
Informations de copyright
Copyright© 2019 Ferrata Storti Foundation.
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