Activity-aware essential tremor evaluation using deep learning method based on acceleration data.


Journal

Parkinsonism & related disorders
ISSN: 1873-5126
Titre abrégé: Parkinsonism Relat Disord
Pays: England
ID NLM: 9513583

Informations de publication

Date de publication:
01 2019
Historique:
received: 26 03 2018
revised: 06 07 2018
accepted: 02 08 2018
pubmed: 21 8 2018
medline: 3 3 2020
entrez: 21 8 2018
Statut: ppublish

Résumé

Essential tremor (ET), one of the most common neurological disorders is typically evaluated with validated rating scales which only provide a subjective assessment during a clinical visit, underestimating the fluctuations tremor during different daily activities. Motion sensors have shown favorable performances in both quantifying tremor and voluntary human activity recognition (HAR). To create an automated system of a reference scale using motion sensors supported by deep learning algorithms to accurately rate ET severity during voluntary activities, and to propose an IOTA based blockchain application to share anonymously tremor data. A smartwatch-based tremor monitoring system was used to collect motion data from 20 subjects while they were doing standard tasks. Two neurologists rated ET by Fahn-Tolosa Marin Tremor Rating Scale (FTMTRS). Supported by deep learning techniques, activity classification models (ACMs) and tremor evaluation models (TEMs) were created and algorithms were implemented, to distinguish voluntary human activities and evaluate tremor severity respectively. A practical application example showed that the proposed ACMs can classify six typical activities with high accuracy (89.73%-98.84%) and the results produced by the TEMs are significantly correlated with the FTMTRS ratings of two neurologists (r This study demonstrated that motion sensor data, supported by deep learning algorithms, can be used to classify human activities and evaluate essential tremor severity during different activities.

Sections du résumé

BACKGROUND
Essential tremor (ET), one of the most common neurological disorders is typically evaluated with validated rating scales which only provide a subjective assessment during a clinical visit, underestimating the fluctuations tremor during different daily activities. Motion sensors have shown favorable performances in both quantifying tremor and voluntary human activity recognition (HAR).
OBJECTIVE
To create an automated system of a reference scale using motion sensors supported by deep learning algorithms to accurately rate ET severity during voluntary activities, and to propose an IOTA based blockchain application to share anonymously tremor data.
METHOD
A smartwatch-based tremor monitoring system was used to collect motion data from 20 subjects while they were doing standard tasks. Two neurologists rated ET by Fahn-Tolosa Marin Tremor Rating Scale (FTMTRS). Supported by deep learning techniques, activity classification models (ACMs) and tremor evaluation models (TEMs) were created and algorithms were implemented, to distinguish voluntary human activities and evaluate tremor severity respectively.
RESULT
A practical application example showed that the proposed ACMs can classify six typical activities with high accuracy (89.73%-98.84%) and the results produced by the TEMs are significantly correlated with the FTMTRS ratings of two neurologists (r
CONCLUSION
This study demonstrated that motion sensor data, supported by deep learning algorithms, can be used to classify human activities and evaluate essential tremor severity during different activities.

Identifiants

pubmed: 30122598
pii: S1353-8020(18)30331-6
doi: 10.1016/j.parkreldis.2018.08.001
pii:
doi:

Types de publication

Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

17-22

Informations de copyright

Copyright © 2018. Published by Elsevier Ltd.

Auteurs

Xiaochen Zheng (X)

Department of Industrial Engineering, Universidad Politécnica de Madrid, Madrid, Spain.

Alba Vieira (A)

Neurology Service, Hospital Universitario de Getafe, Getafe, Madrid, Spain.

Sergio Labrador Marcos (SL)

Neurology Service, Hospital Universitario de Getafe, Getafe, Madrid, Spain.

Yolanda Aladro (Y)

Neurology Service, Hospital Universitario de Getafe, Getafe, Madrid, Spain.

Joaquín Ordieres-Meré (J)

Department of Industrial Engineering, Universidad Politécnica de Madrid, Madrid, Spain. Electronic address: j.ordieres@upm.es.

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