Subcutaneous auto-administration of trastuzumab following therapeutic education: A case report.


Journal

Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
ISSN: 1477-092X
Titre abrégé: J Oncol Pharm Pract
Pays: England
ID NLM: 9511372

Informations de publication

Date de publication:
Sep 2019
Historique:
pubmed: 22 8 2018
medline: 20 11 2019
entrez: 22 8 2018
Statut: ppublish

Résumé

Trastuzumab is a monoclonal antibody used to treat human epidermal growth receptor 2 positive (HER2+) breast cancers either by itself or in combination with other chemotherapy medication. Marketing authorization was granted for a subcutaneous form of the antibody in 2014. In this case report, we discuss our experience with a patient who took part in a therapeutic education program on self-administration of trastuzumab. We demonstrate that these types of self-administered injections are not only possible but also are toxicity-free. Based on the tolerance data and our patient's experience, we propose that the current regulations be relaxed regarding the availability of trastuzumab subcutaneous form in order to develop a cheaper "city scheme," i.e. self-administered injections.

Identifiants

pubmed: 30126339
doi: 10.1177/1078155218792364
doi:

Substances chimiques

Antineoplastic Agents, Immunological 0
ERBB2 protein, human EC 2.7.10.1
Receptor, ErbB-2 EC 2.7.10.1
Trastuzumab P188ANX8CK

Types de publication

Case Reports Journal Article

Langues

eng

Sous-ensembles de citation

IM

Pagination

1523-1525

Auteurs

Marine Deppenweiler (M)

1 Department of Pharmacy, Institut Bergonié, Bordeaux, France.

Marc Debled (M)

2 Department of Oncology, Institut Bergonié, Bordeaux, France.

Jean-Luc Robquin (JL)

1 Department of Pharmacy, Institut Bergonié, Bordeaux, France.

Barbara Lortal-Canguilhem (B)

1 Department of Pharmacy, Institut Bergonié, Bordeaux, France.

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Classifications MeSH