Subcutaneous auto-administration of trastuzumab following therapeutic education: A case report.
Breast cancer
monoclonal antibodies
self-administration
Journal
Journal of oncology pharmacy practice : official publication of the International Society of Oncology Pharmacy Practitioners
ISSN: 1477-092X
Titre abrégé: J Oncol Pharm Pract
Pays: England
ID NLM: 9511372
Informations de publication
Date de publication:
Sep 2019
Sep 2019
Historique:
pubmed:
22
8
2018
medline:
20
11
2019
entrez:
22
8
2018
Statut:
ppublish
Résumé
Trastuzumab is a monoclonal antibody used to treat human epidermal growth receptor 2 positive (HER2+) breast cancers either by itself or in combination with other chemotherapy medication. Marketing authorization was granted for a subcutaneous form of the antibody in 2014. In this case report, we discuss our experience with a patient who took part in a therapeutic education program on self-administration of trastuzumab. We demonstrate that these types of self-administered injections are not only possible but also are toxicity-free. Based on the tolerance data and our patient's experience, we propose that the current regulations be relaxed regarding the availability of trastuzumab subcutaneous form in order to develop a cheaper "city scheme," i.e. self-administered injections.
Identifiants
pubmed: 30126339
doi: 10.1177/1078155218792364
doi:
Substances chimiques
Antineoplastic Agents, Immunological
0
ERBB2 protein, human
EC 2.7.10.1
Receptor, ErbB-2
EC 2.7.10.1
Trastuzumab
P188ANX8CK
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM