Successful Implementation of a Shared Medical Appointment Model for Hepatitis C Treatment at a Community Health Center.


Journal

Journal of community health
ISSN: 1573-3610
Titre abrégé: J Community Health
Pays: Netherlands
ID NLM: 7600747

Informations de publication

Date de publication:
02 2019
Historique:
pubmed: 23 8 2018
medline: 15 2 2020
entrez: 23 8 2018
Statut: ppublish

Résumé

Highly efficacious direct acting antiviral (DAA) therapy for treatment of Hepatitis C Virus (HCV) infection is largely inaccessible to communities facing a shortage of available specialist providers. Though less demanding than previous interferon regimens, DAA therapy requires patients to adhere to 8-12 weeks of daily treatment, which can be challenging for some patient populations. Duffy Health Center, located on Cape Cod, Massachusetts, provides integrated medical, mental health and case management services to people who are homeless or at risk for homelessness. The goal of this manuscript is to evaluate the outcomes of treatment of HCV infection with a shared medical appointment (SMA) model. The primary outcome was sustained virologic response (SVR-12), or HCV RNA ≤ 15 IU/mL at 12 weeks post-treatment. There were 102 patients recruited, with a total of 104 treatments administered. Over three-fourths of patients who attended one SMA visit (78 of 102) continued in SMA for the duration of treatment. Of these patients opting for SMA, 99% (77 of 78) completed the full treatment course, and 91% (71 of 78) of SMA patients achieved SVR-12. DAA therapy provided by non-specialist providers using the SMA model yielded comparable response rates to those achieved by specialist providers, and has the potential to substantially increase access to HCV treatment for patient populations within high-risk communities.

Identifiants

pubmed: 30132236
doi: 10.1007/s10900-018-0568-z
pii: 10.1007/s10900-018-0568-z
pmc: PMC6330118
mid: NIHMS994628
doi:

Substances chimiques

Antiviral Agents 0

Types de publication

Journal Article Research Support, N.I.H., Extramural Research Support, U.S. Gov't, P.H.S.

Langues

eng

Sous-ensembles de citation

IM

Pagination

169-171

Subventions

Organisme : NCATS NIH HHS
ID : KL2 TR002545
Pays : United States
Organisme : NIDA NIH HHS
ID : R25 DA037190
Pays : United States

Références

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pubmed: 28395004
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pubmed: 29310928
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pubmed: 29426304
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pubmed: 28785771
BMJ. 2017 Aug 30;358:j4034
pubmed: 28855156
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pubmed: 28426313
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pubmed: 26171595
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pubmed: 26312999
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pubmed: 29702515
J Clin Transl Hepatol. 2017 Jun 28;5(2):130-133
pubmed: 28660150

Auteurs

Jacqueline Hodges (J)

Tufts University School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA. jchodges03@gmail.com.

Jessica Reyes (J)

Tufts University School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA.

Joyce Campbell (J)

Duffy Health Center, 94 Main St, Hyannis, MA, 02601, USA.

Wesley Klein (W)

Duffy Health Center, 94 Main St, Hyannis, MA, 02601, USA.

Alysse Wurcel (A)

Tufts University School of Medicine, 145 Harrison Ave, Boston, MA, 02111, USA.
Tufts Medical Center, 800 Washington St, Boston, MA, 02111, USA.

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Classifications MeSH