Chronic vulvovaginitis caused by Candida dubliniensis in an immunologically competent adult female.
None
fluconazole resistance
vulvovaginitis
Journal
International journal of STD & AIDS
ISSN: 1758-1052
Titre abrégé: Int J STD AIDS
Pays: England
ID NLM: 9007917
Informations de publication
Date de publication:
01 2019
01 2019
Historique:
pubmed:
2
9
2018
medline:
23
7
2019
entrez:
2
9
2018
Statut:
ppublish
Résumé
Candida, a commensal dimorphic fungus, is the most common microorganism that causes opportunistic fungal infections worldwide. It can cause diseases ranging from superficial mucosal infections to disseminated, systemic life-threatening infections. Among Candida species, Candida albicans is the most common infectious agent. Nowadays, non- albicans Candida species are also emerging as significant pathogens. Candida dubliniensis has been implicated as a causative agent of oral candidiasis in HIV-infected individuals but has also been recovered from HIV non-infected individuals with oral candidiasis and rarely from the genital tract of women with vaginitis. Such cases have been under-reported due to phenotypic resemblance to C. albicans. The majority of C. dubliniensis clinical isolates tested to date have been susceptible to fluconazole, but they tend to develop resistance rapidly. Here, we report a case of chronic vulvovaginitis due to C. dubliniensis not responding to standard doses of fluconazole.
Identifiants
pubmed: 30170531
doi: 10.1177/0956462418792113
doi:
Substances chimiques
Antifungal Agents
0
Fluconazole
8VZV102JFY
Linezolid
ISQ9I6J12J
Types de publication
Case Reports
Journal Article
Langues
eng
Sous-ensembles de citation
IM