Two new xanthones and cytotoxicity from the bark of Garcinia schomburgkiana.
Clusiaceae
Cytotoxicity
Garcinia schomburgkiana
Xanthone
Journal
Journal of natural medicines
ISSN: 1861-0293
Titre abrégé: J Nat Med
Pays: Japan
ID NLM: 101518405
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
25
05
2018
accepted:
17
08
2018
pubmed:
2
9
2018
medline:
29
5
2019
entrez:
2
9
2018
Statut:
ppublish
Résumé
Two new xanthone derivatives, named schomburgones A (1) and B (2), along with eight known compounds, including xanthones (3-8) and anthraquinones (9-10) were isolated from the bark of Garcinia schomburgkiana. Their structures were determined by spectroscopic analysis especially 1D and 2D NMR spectroscopies. All isolated compounds were evaluated for their cytotoxicity against five cancer cell lines (KB, HeLa S-3, HT-29, MCF-7 and HepG-2). Compounds 3-6 and 8 showed good cytotoxicity against all the five cancer cell lines with IC
Identifiants
pubmed: 30171417
doi: 10.1007/s11418-018-1240-8
pii: 10.1007/s11418-018-1240-8
pmc: PMC6326088
doi:
Substances chimiques
Cytotoxins
0
Xanthones
0
Types de publication
Journal Article
Langues
eng
Sous-ensembles de citation
IM
Pagination
257-261Références
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