A successful multidisciplinary approach for treatment and for preserving the reproductive potential in a rare case of acute lymphocytic leukemia during pregnancy.
Adult
Antineoplastic Combined Chemotherapy Protocols
/ therapeutic use
Cesarean Section
Consolidation Chemotherapy
/ methods
Cryopreservation
/ methods
Female
Fertility Preservation
/ methods
Fetal Growth Retardation
Humans
Induction Chemotherapy
/ methods
Infant, Newborn
Male
Methotrexate
/ therapeutic use
Ovariectomy
/ methods
Ovary
Patient Care Team
Precursor B-Cell Lymphoblastic Leukemia-Lymphoma
/ therapy
Pregnancy
Pregnancy Complications, Neoplastic
/ therapy
Leukemia
artificial ovary
autotransplantation
oncofertility
ovarian tissue cryopreservation
pregnancy
Journal
Gynecological endocrinology : the official journal of the International Society of Gynecological Endocrinology
ISSN: 1473-0766
Titre abrégé: Gynecol Endocrinol
Pays: England
ID NLM: 8807913
Informations de publication
Date de publication:
Feb 2019
Feb 2019
Historique:
pubmed:
5
9
2018
medline:
14
8
2019
entrez:
5
9
2018
Statut:
ppublish
Résumé
Leukemia in pregnancy is a rare condition with the prevalence of 1 in 75,000-100,000 pregnancies. In this case report, we present a successful multidisciplinary management strategy for treatment and for preserving the reproductive potential in a rare case of acute lymphocytic leukemia (ALL) during pregnancy. Several complex challenges existed and necessitated a multidisciplinary approach with strong coordination and collaboration between oncologists, gynecologists, reproductive cryobiologists, obstetricians, and neonatologists in order to improve the maternal and fetal outcome. Pregnancy in the second trimester is neither a contraindication for ALL treatment nor for emergency fertility preservation via ovarian tissue extraction and further cryopreservation.
Identifiants
pubmed: 30179055
doi: 10.1080/09513590.2018.1498833
doi:
Substances chimiques
Methotrexate
YL5FZ2Y5U1
Types de publication
Journal Article
Langues
eng