Distribution of preoperative and postoperative astigmatism in a large population of patients undergoing cataract surgery in the UK.


Journal

The British journal of ophthalmology
ISSN: 1468-2079
Titre abrégé: Br J Ophthalmol
Pays: England
ID NLM: 0421041

Informations de publication

Date de publication:
07 2019
Historique:
received: 05 02 2018
revised: 17 07 2018
accepted: 07 08 2018
pubmed: 8 9 2018
medline: 7 3 2020
entrez: 8 9 2018
Statut: ppublish

Résumé

To assess the prevalence and severity of preoperative and postoperative astigmatism in patients with cataract in the UK. Data from 8 UK National Health Service ophthalmology clinics using MediSoft electronic medical records (EMRs). Retrospective cohort study. Eyes from patients aged ≥65 years undergoing cataract surgery were analysed. For all eyes, preoperative (corneal) astigmatism was evaluated using the most recent keratometry measure within 2 years prior to surgery. For eyes receiving standard monofocal intraocular lens (IOLs), postoperative refractive astigmatism was evaluated using the most recent refraction measure within 2-12 months postsurgery. A power vector analysis compared changes in the astigmatic 2-dimensional vector (J Eligible eyes included in the analysis were 110 468. Of these, 78% (n=85 650) had preoperative (corneal) astigmatism ≥0.5 dioptres (D), 42% (n=46 003) ≥1.0 D, 21% (n=22 899) ≥1.5 D and 11% (n=11 651) ≥2.0 D. After surgery, the refraction cylinder was available for 39 744 (36%) eyes receiving standard monofocal IOLs, of which 90% (n=35 907) had postoperative astigmatism ≥0.5 D and 58% (n=22 886) ≥1.0 D. Visual acuity tended to worsen postoperatively with increased astigmatism (ρ=-0.44, P<0.01). There is a significant burden of preoperative astigmatism in the UK cataract population. The available refraction data indicate that this burden is not reduced after surgery with implantation of standard monofocal IOLs. Measures should be taken to improve visual outcomes of patients with astigmatic cataract by simultaneously correcting astigmatism during cataract surgery.

Identifiants

pubmed: 30190365
pii: bjophthalmol-2018-312025
doi: 10.1136/bjophthalmol-2018-312025
pmc: PMC6591741
doi:

Types de publication

Journal Article Research Support, Non-U.S. Gov't

Langues

eng

Sous-ensembles de citation

IM

Pagination

993-1000

Informations de copyright

© Author(s) (or their employer(s)) 2019. Re-use permitted under CC BY-NC. No commercial re-use. See rights and permissions. Published by BMJ.

Déclaration de conflit d'intérêts

Competing interests: IQVIA received funding from Alcon Laboratories, Inc to conduct this study. ACD and DFA declare no competing interests. MD and MSK were employees of Alcon Laboratories Inc at the time of research. FE and CPV are employees of Alcon Management SA. CM and LZ are employees of IQVIA.

Références

J Cataract Refract Surg. 2015 Jun;41(6):1256-63
pubmed: 26189381
Eye (Lond). 2009 Jan;23(1):38-49
pubmed: 18034196
J Cataract Refract Surg. 2010 Aug;36(8):1323-9
pubmed: 20656155
J Cataract Refract Surg. 2011 Mar;37(3):454-60
pubmed: 21333869
J Cataract Refract Surg. 2012 Jul;38(7):1181-6
pubmed: 22727287
Br J Ophthalmol. 2002 Dec;86(12):1458-9
pubmed: 12446403
Acta Ophthalmol Scand. 2000 Dec;78(6):642-6
pubmed: 11167223
J Cataract Refract Surg. 2011 Oct;37(10):1751-5
pubmed: 21840163
Ophthalmic Physiol Opt. 2014 May;34(3):267-94
pubmed: 24635572
J Cataract Refract Surg. 2010 Sep;36(9):1479-85
pubmed: 20692558
Invest Ophthalmol Vis Sci. 2011 Dec 28;52(13):9651-7
pubmed: 22110083
Curr Opin Ophthalmol. 2013 Jan;24(1):30-4
pubmed: 23197264
Ophthalmology. 2016 Feb;123(2):275-86
pubmed: 26601819
J Cataract Refract Surg. 2016 Jan;42(1):102-9
pubmed: 26948784
Eur J Ophthalmol. 2014 Jul-Aug;24(4):494-500
pubmed: 24366768
Can J Ophthalmol. 2014 Jun;49(3):297-303
pubmed: 24862779
J Cataract Refract Surg. 2001 Jan;27(1):80-5
pubmed: 11165859
Ulster Med J. 2017 Jan;86(1):25-27
pubmed: 28298709
J Cataract Refract Surg. 2008 Apr;34(4):601-7
pubmed: 18361982
Br J Ophthalmol. 2009 Oct;93(10):1307-12
pubmed: 19429581
Eye (Lond). 2010 May;24(5):894-900
pubmed: 19680278
J Ophthalmol. 2014;2014:536412
pubmed: 24991429
BMC Ophthalmol. 2012 Aug 15;12:41
pubmed: 22894651

Auteurs

Alexander C Day (AC)

The NIHR Biomedical Research Centre, Moorfields Eye Hospital NHS Foundation Trust and UCL Institute of Ophthalmology, London, UK.
Cataract Service, Moorfields Eye Hospital, London, UK.

Mukesh Dhariwal (M)

Alcon Laboratories Inc, Fort Worth, Texas, USA.

Michael S Keith (MS)

Alcon Laboratories Inc, Fort Worth, Texas, USA.

Frank Ender (F)

Alcon Management SA, Geneva, Switzerland.

Caridad Perez Vives (C)

Alcon Management SA, Geneva, Switzerland.

Cristiana Miglio (C)

Centre of Excellence for Retrospective Studies, IQVIA, London, UK.

Lu Zou (L)

Centre of Excellence for Retrospective Studies, IQVIA, London, UK.

David F Anderson (DF)

Ophthalmology, University Hospital Southampton NHS Foundation Trust, Southampton, UK davidanderson3@nhs.net.
Ophthalmology, University of Southampton, Southampton, UK.

Articles similaires

[Redispensing of expensive oral anticancer medicines: a practical application].

Lisanne N van Merendonk, Kübra Akgöl, Bastiaan Nuijen
1.00
Humans Antineoplastic Agents Administration, Oral Drug Costs Counterfeit Drugs

Smoking Cessation and Incident Cardiovascular Disease.

Jun Hwan Cho, Seung Yong Shin, Hoseob Kim et al.
1.00
Humans Male Smoking Cessation Cardiovascular Diseases Female
Humans United States Aged Cross-Sectional Studies Medicare Part C
1.00
Humans Yoga Low Back Pain Female Male

Classifications MeSH