Contrast Media-Induced Nephropathy in Patients with Unruptured Cerebral Aneurysm After Coiling Endovascular Treatment.
Aged
Cerebral Angiography
/ methods
Computed Tomography Angiography
/ methods
Contrast Media
/ adverse effects
Embolization, Therapeutic
/ adverse effects
Endovascular Procedures
/ adverse effects
Female
Humans
Intracranial Aneurysm
/ therapy
Male
Nervous System Diseases
/ chemically induced
Neurosurgical Procedures
/ adverse effects
Retrospective Studies
Risk Factors
Treatment Outcome
Triiodobenzoic Acids
/ adverse effects
Cerebral angiography
Contrast media
Intracranial aneurysm
Nephropathy
Journal
World neurosurgery
ISSN: 1878-8769
Titre abrégé: World Neurosurg
Pays: United States
ID NLM: 101528275
Informations de publication
Date de publication:
Jan 2019
Jan 2019
Historique:
received:
06
07
2018
revised:
24
08
2018
accepted:
27
08
2018
pubmed:
10
9
2018
medline:
3
1
2019
entrez:
10
9
2018
Statut:
ppublish
Résumé
The endovascular coiling procedure to treat cerebral aneurysms using contrast media has become more popular. However, studies of the incidence of, and risk factors for, contrast media-induced nephropathy (CIN) after coiling procedures have been limited. Thus, we evaluated the incidence and risk factors for CIN in patients who had undergone cerebral aneurysmal coiling procedures. We retrospectively reviewed the electric medical records of 380 patients who had undergone cerebral aneurysmal coiling treatment under general anesthesia. CIN was defined as an absolute increase in serum creatinine (≥0.5 mg/dL) or a relative increase (≥25%) in the baseline serum creatinine value at 48-72 hours after exposure to a contrast agent. Elective cerebral aneurysmal coiling procedures were performed in 230 patients. Of the 230 patients, CIN developed in 13 (5.6%). The presence of diabetes mellitus (30.8% vs. 9.7%; P = 0.040) and patient age >75 years (30.8% vs. 6.5%; P = 0.012) were risk factors for CIN. Our study has demonstrated that the incidence of CIN in patients undergoing elective cerebral aneurysmal coiling procedures is ∼6.0%. We also identified underlying diabetes mellitus and advanced age (≥75 years) as potential risk factors.
Sections du résumé
BACKGROUND
BACKGROUND
The endovascular coiling procedure to treat cerebral aneurysms using contrast media has become more popular. However, studies of the incidence of, and risk factors for, contrast media-induced nephropathy (CIN) after coiling procedures have been limited. Thus, we evaluated the incidence and risk factors for CIN in patients who had undergone cerebral aneurysmal coiling procedures.
METHODS
METHODS
We retrospectively reviewed the electric medical records of 380 patients who had undergone cerebral aneurysmal coiling treatment under general anesthesia. CIN was defined as an absolute increase in serum creatinine (≥0.5 mg/dL) or a relative increase (≥25%) in the baseline serum creatinine value at 48-72 hours after exposure to a contrast agent.
RESULTS
RESULTS
Elective cerebral aneurysmal coiling procedures were performed in 230 patients. Of the 230 patients, CIN developed in 13 (5.6%). The presence of diabetes mellitus (30.8% vs. 9.7%; P = 0.040) and patient age >75 years (30.8% vs. 6.5%; P = 0.012) were risk factors for CIN.
CONCLUSIONS
CONCLUSIONS
Our study has demonstrated that the incidence of CIN in patients undergoing elective cerebral aneurysmal coiling procedures is ∼6.0%. We also identified underlying diabetes mellitus and advanced age (≥75 years) as potential risk factors.
Identifiants
pubmed: 30196168
pii: S1878-8750(18)31992-2
doi: 10.1016/j.wneu.2018.08.206
pii:
doi:
Substances chimiques
Contrast Media
0
Triiodobenzoic Acids
0
iodixanol
HW8W27HTXX
Types de publication
Journal Article
Multicenter Study
Langues
eng
Sous-ensembles de citation
IM
Pagination
e39-e44Informations de copyright
Copyright © 2018 Elsevier Inc. All rights reserved.