Nrf2-Mediated System x


Journal

Molecular neurobiology
ISSN: 1559-1182
Titre abrégé: Mol Neurobiol
Pays: United States
ID NLM: 8900963

Informations de publication

Date de publication:
May 2019
Historique:
received: 07 03 2018
accepted: 03 09 2018
pubmed: 14 9 2018
medline: 14 8 2019
entrez: 14 9 2018
Statut: ppublish

Résumé

HIV-associated neurocognitive disorders (HANDs) affect a large part of HIV-infected patients, despite highly active antiretroviral therapy. HANDs occur in the absence of a direct infection of neurons. Nevertheless, viral proteins (e.g., Tat) are capable to cause neuronal dysfunction via oxidative stress, but the cellular pathways leading to HANDs are not yet fully defined. Here, we investigated the effects of Tat on Nrf2-mediated antioxidant response and system x

Identifiants

pubmed: 30209772
doi: 10.1007/s12035-018-1343-y
pii: 10.1007/s12035-018-1343-y
doi:

Substances chimiques

Amino Acid Transport System y+ 0
Glutamates 0
NF-E2-Related Factor 2 0
Neurotoxins 0
RNA, Messenger 0
tat Gene Products, Human Immunodeficiency Virus 0

Types de publication

Journal Article

Langues

eng

Pagination

3796-3806

Subventions

Organisme : EURIPRED
ID : 312661
Organisme : Excellence Departments, MIUR-Italy
ID : ARTICOLO 1, COMMI 314 - 337 LEGGE 232/2016

Commentaires et corrections

Type : ErratumIn

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Auteurs

Roberta Mastrantonio (R)

Department of Sciences, University "ROMA TRE", Rome, Italy.

Veronica D'Ezio (V)

Department of Sciences, University "ROMA TRE", Rome, Italy.

Marco Colasanti (M)

Department of Sciences, University "ROMA TRE", Rome, Italy.

Tiziana Persichini (T)

Department of Sciences, University "ROMA TRE", Rome, Italy. tiziana.persichini@uniroma3.it.

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Classifications MeSH